Results 241 to 250 of about 377,815 (340)

Additional file 3 of Relevance of porcine intestinal organoids as a surrogate for animal experimentation: application to the investigation of host–virus interactions during porcine coronavirus infection

Percevault, Ludivine, Tranchevent, Léon-Charles, Bigault, Lionel, Berthaud, Maxime, Le Gloahec, Damien, Lucas, Pierrick, Carnet, Flora, Le Roux, Aurélie, Le Diguerher, Gérald, Paboeuf, Frédéric, Dory, Daniel, Blanchard, Yannick, Grasland, Béatrice, Contrant, Maud   +13 more
openalex   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Restructuring postgraduate curriculum in pharmacology: Time to incorporate alternatives to animal experimentation.

Indian J Pharmacol, 2016
Khilnani G, Khilnani AK.
europepmc   +1 more source

Animal Experimentation: Working Towards a Paradigm Change

, 2019
Herrmann, Kathrin, Jayne, Kimberley
openalex   +2 more sources

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Protection of Animals and Animal Experimentation: A Survey of Scientific Experts

, 1983
Norbert Lagoni, Joachim Fiebelkorn, H.‐J. Wormuth   +2 more
openalex   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Strengthening translational preclinical research through confirmatory multi-laboratory studies. [PDF]

Front Med (Lausanne)
Rotter SC, Arroyo-Araujo M, Drude NI, Pellegrini P, Kobold S, Richter GHS, Müller OJ, Bruder D, Riecken LB, Gerlach B, Schuler L, Salbach-Hirsch J, Dalloul I, Kühn S, Wilcke JC, Toelch U.   +15 more
europepmc   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Are we going to allow the last nail on the coffin of animal experimentation to be nailed?

J Pharmacol Pharmacother, 2012
Gitanjali B.
europepmc   +1 more source