Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
3Rs principles for biomedical research in Africa: Evidence, challenges, early career researchers' perspectives, and pathways for One Health research governance. [PDF]
Olaniyan OF, Dumbuya M.
europepmc +1 more source
Life-history traits associated to West Nile virus seroprevalence in wild birds: Lessons from the recent outbreaks in Spain. [PDF]
Martín-López AI +9 more
europepmc +1 more source
How ignoring the harm of killing undermines the ethical legitimacy of animal research: a case study from Switzerland. [PDF]
Rodriguez C, Blattner CE, Martin AK.
europepmc +1 more source
Correction to: Could hair cortisol in free-ranging cattle be a proxy of wolf predation patterns? [PDF]
europepmc +1 more source
Animal Experimentation in Africa: Legislation and Guidelines
Animal experimentation is common in Africa, despite the fact that legislation in the field is scarce. The current chapter is aimed at investigating and reviewing shortfalls in the legislation and guidelines concerning animal welfare in general, and ...
Jann Hau +2 more
exaly +2 more sources
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