Results 31 to 40 of about 377,815 (340)
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Frontiers in Cellular and Infection MicrobiologyIntroductionMethicillin-resistant Staphylococcus aureus (MRSA) infections have become arduous to treat due to their capacity to form biofilms, develop persistence, and exhibit significant antimicrobial resistance.
Priyanka +11 more
doaj +1 more source
Laboratory animal: biological reagent or living being?
Brazilian Journal of Medical and Biological Research, 2014 The duties of humans toward non-human animals and their rights in society have been debated for a long time. However, a discussion on the terminology used for the identification of laboratory animals is usually not considered, although the employment of ...
C.V.P. Cardoso, A.E.C.C. de Almeida
doaj +1 more source
Long-term vascular access ports as a means of sedative administration in a rodent fMRI survival model [PDF]
, 2011 The purpose of this study is to develop a rodent functional magnetic resonance imaging (fMRI) survival model with the use of heparin-coated vascular access devices.
Cho, Younghoon R +7 more
core +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Animals in Moral Limbo: How Literary Pigs May Help Lab-Generated Ones
Animals, 2020 When considering that artistic and literary artifacts reflect the cultural views and mores of a particular time period, there is a significant misalignment between stories depicting increased moral status of pigs (e.g., vis-à-vis human-porcine ...
Nancy Tuck
doaj +1 more source
Building a Science of Animal Minds: Lloyd Morgan, Experimentation, and Morgan’s Canon [PDF]
, 2017 Conwy Lloyd Morgan (1852–1936) is widely regarded as the father of modern comparative psychology. Yet, Morgan initially had significant doubts about whether a genuine science of comparative psychology was even possible, only later becoming more ...
Fitzpatrick, Simon, Goodrich, Grant
core
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Confronting the bias towards animal experimentation (animal methods bias)
Frontiers in Drug DiscoveryLaws and policies are in place around the world to promote the replacement and reduction of nonhuman animals in science. These principles are rooted not just in ethical considerations for animals, but also in scientific considerations regarding the ...
Catharine E. Krebs +2 more
doaj +1 more source