Results 101 to 110 of about 2,326,634 (293)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Оптимізація біотехнологічних підходів у системі збереження генофонду свиней миргородської породи

open access: yesФактори експериментальної еволюції організмів, 2014
Aims. Gene pool preservation endangered, indigenous pig breeds requires using methods modern biotechnology and genetic. Create a cryocollection Mirgorodska breed pigs viable oocytes and DNA bank for the development of scientific methods of maintenance ...
О. І. Метлицька   +5 more
doaj  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Animal Genetics

open access: yes, 2022
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Weickhardt, Leonard W.
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

The Genetic Architecture of Domestication in Animals.

open access: yesBioinformatics and biology insights, 2015
Domestication has been essential to the progress of human civilization, and the process itself has fascinated biologists for hundreds of years. Domestication has led to a series of remarkable changes in a variety of plants and animals, in what is termed the "domestication phenotype." In domesticated animals, this general phenotype typically consists of
openaire   +4 more sources

Exploring the potential of hierarchical generalized linear models in animal breeding and genetics

open access: yes, 2013
Complex problems do not always require complex tools, and searching for these simple solutions is what makes science really exciting. Hypothesis testing and prediction in animal breeding and genetics can be rather complex because they require modelling ...
Sveriges lantbruksuniversitet.   +1 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

BIOMETRICS SOCIETY AND THE PROGRESS OF ANIMAL SCIENCE IN ROMANIA [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2014
Romanian animal, agricultural and biological sciences were seriously damaged in the period 1948-1964 by the introduction of the Stalinsko- lasenko approach in the field of Genetics and by an empiric-pragmatic approach of agricultural theory.
Condrea DRAGANESCU
doaj  

Home - About - Disclaimer - Privacy