Results 91 to 100 of about 521,393 (302)

Plasticity and repeatability in spring migration and parturition dates with implications for annual reproductive success

, 2023
<p>Code and data for Laforge et al 2023 (Journal of Animal Ecology) - Plasticity and repeatability in spring migration and parturition dates with implications for annual reproductive success</p ...
Vander Wal, Eric, Webber, Quinn M.R., Laforge, Michel P.   +2 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Captivity alters behaviour but not seasonal brain size change in semi-naturally housed shrews

Royal Society Open Science
Captivity, frequently used in animal research, can profoundly alter brain size, cognitive abilities and activity levels. Critically, persistent exposure to stressors in captive environments can lead to chronic stress and subsequently to a range of health
Cecilia Baldoni, Konstantinos Raptis, Marina Farantouri, Ivan Lenzi, Ka Sing Lim, Myles H. M. Menz, Marion Muturi, Marco Reisert, Maria Alejandra Bedoya Duque, William R. Thomas, Liliana M. Dávalos, John D. Nieland, Dominik von Elverfeldt, Dina K. N. Dechmann   +13 more
doaj   +1 more source

Going, Going, Gone: Is Animal Migration Disappearing

PLoS Biology, 2008
Many of the world's migratory animals are in decline. This essay explores the unique scientific and political challenges of protecting migratory species while they are still common.
Wilcove, David S., Wikelski, Martin
openaire   +6 more sources

Energetic and Biomechanical Constraints on Animal Migration Distance

, 2011
Animal migration is one of the great wonders of nature, but the factors that determine how far migrants travel remain poorly understood. We present a new quantitative model of animal migration and use it to describe the maximum migration distance of ...
Hou, Chen, Gillooly, James F., Chen Hou, James F. Gillooly, Andrew M. Hein, Hein, Andrew M.   +5 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Gaps in modelling animal migration with evolutionary game theory: infection can favour the loss of migration. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2023
Shaw AK, Torstenson M, Craft ME, Binning SA.   +3 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

First deployment of IoT tracking devices on Common swift Apus apus: a pilot study

Avocetta
Five breeding adults of Common swift Apus apus from a north Italian colony were equipped with lightweight (1.2 g) tracking devices based on IoT (Internet of Things) technology, collecting location data and transmitting them through the Sigfox network of
Michelangelo Morganti, Milo Manica, Daniela Casola, Lorenzo Colombo, Alessandra Stocchetti, Wolfgang Fiedler, Martin Wikelski, Klaudia Witte, Timm Alexander Wild   +8 more
doaj   +1 more source