Results 81 to 90 of about 507,229 (262)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Forced Migration Review, 2015 Harm to animals resulting from forced migration of people is intricately interwoven with and contingent upon the simultaneous suffering of humans.
Beirne, P, Kelty-Huber, C
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Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
TRANSITIONS NEAR RESOURCE MAXIMAS IN THE MODEL OF ANIMAL MIGRATION
Вестник Кемеровского государственного университета, 2015 The author undertakes an attempt to find the numerically prospective periodic solutions near two maximas of resource function in a mathematical model of animal migration.
V. V. Machulis
doaj
Environmental DNACoastal environments serve as essential nursing, feeding, and spawning grounds for commercially and ecologically important fish species, some of which use nearshore habitats as transitional steps in their ontogenetic migration.
Marianne Lolivier +5 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
ParasitologyLarge gulls (Laridae) have expanded from coastal regions into inland Central Europe, where they increasingly exploit fishponds, landfills, and urban habitats.
Jiljí Sitko, Petr Heneberg
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The Migration of Insect Vectors of Plant and Animal Viruses
, 2006 Publisher Summary This chapter summarizes the conceptual framework that distinguishes migration from other types of movement, and briefly outlines some of the methodologies used to study long-range migration of insect vectors. Several case studies of vector migration, particularly ones illustrating recent progress have been presented.
Reynolds, D. R. +2 more
openaire +2 more sources