Results 81 to 90 of about 521,393 (302)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
The ErbB2 receptor and breast carcinoma cell migration : memo is a novel mediator of cell motility [PDF]
, 2003 The ErbB family of receptor tyrosine kinases play important role in normal physiological processes occurring during development; moreover, their deregulated expression has been implicated in human cancer. Cancer patients, whose tumors have alterations in
Marone, Romina
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Introducing a unique animal ID and digital life history museum for wildlife metadata
Methods in Ecology and EvolutionOver the past five decades, a large number of wild animals have been individually identified by various observation systems and/or temporary tracking methods, providing unparalleled insights into their lives over both time and space.
Martin Wikelski +40 more
doaj +1 more source
Animal migration research takes wing [PDF]
Current Biology, 2018 In the beginning there was great confusion about animal migration. Aristotle, noting that the types of birds around him changed with the seasons, concluded that summer redstarts turned into robins at the onset of winter, and that garden warblers became blackcaps [1]. Others thought that birds disappear in winter because they hibernate submerged in mud.
openaire +2 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
move2: R package for processing movement data
Methods in Ecology and EvolutionStudying animal movement is key to understanding ecological processes and studying the impacts of global change. The pivotal importance of collecting movement data drives technological development, and as a consequence, movement trajectories are gathered
Bart Kranstauber +2 more
doaj +1 more source
Individual migration patterns of Eurasian golden ploversPluvialis apricariabreeding in Swedish Lapland; examples of cold spell-induced winter movements [PDF]
, 2015 Tracking studies normally focus on long-distance migrants, meaning that our understanding about short-distance migration remains limited. In this study, we present the first individual tracks of the Eurasian golden plover Pluvialis apricaria, a short ...
Flores, Manuel +8 more
core +1 more source
, 2023 Ongoing environmental changes alter how natural selection shapes animal migration. Understanding how these changes play out theoretically can be done using evolutionary game theoretic (EGT) approaches, such as looking for evolutionarily stable strategies.
Sandra A. Binning (12510488) +3 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source