Results 71 to 80 of about 521,393 (302)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Simple behavioural rules can explain the complex migration patterns of monarch butterflies [PDF]

Royal Society Open Science
Many animals undertake seasonal migrations, yet the mechanisms by which they navigate remain poorly understood. For example, North American monarch butterflies (Danaus plexippus) travel upwards of 4500 km to specific overwintering sites in central Mexico.
Mitchell J. Kendzel, Lance A. Waller, Jacobus C. de Roode   +2 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Different Kind of Hunt: Image Hunting in Three Travel Stories

Caliban: French Journal of English Studies, 2018
Nous proposons de rapprocher trois récits, en partie autobiographiques, de Peter Matthiessen, Doug Peacock et Alan Tennant, auteurs américains de la période contemporaine. Dans ces textes, l'aventure tient de la quête.
Céline Rolland Nabuco
doaj   +1 more source

Distribution and Numbers of Three Globally Threatened Waterbird Species Wintering in Morocco: The Common Pochard, Marbled Teal, and White-Headed Duck

International Journal of Zoology, 2021
Morocco plays a key role in the life of many migratory birds and their survival, thanks to the diversity and richness of its ecosystems. The International Waterbird Census (IWC) has been regularly implemented in Morocco since 1983. Thanks to this program,
Asmaâ Ouassou, Mohamed Dakki, Mohammed-Aziz El Agbani, Abdeljebbar Qninba, R’himou El Hamoumi   +4 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Remote Sensing Data Reveal a Significant Reduction in the Area of the Nesting Habitat of Rafetus euphraticus in the Tigris River, Southeastern Turkey

Ecology and Evolution
The Euphrates Softshell Turtle (Rafetus euphraticus) is an endangered freshwater turtle native to the Tigris‐Euphrates river system. Habitat destruction caused by dams and sand mining poses a major threat to the species.
Murat Biricik, Kamran Safi, Şemsettin Turğa   +2 more
doaj   +1 more source

Mechanisms and Consequences of Partial Migration in Insects

Frontiers in Ecology and Evolution, 2019
Partial migration, where a proportion of a population migrates, while other individuals remain resident, is widespread across most migratory lineages.
Myles H. M. Menz, Myles H. M. Menz, Myles H. M. Menz, Myles H. M. Menz, Don R. Reynolds, Don R. Reynolds, Boya Gao, Boya Gao, Gao Hu, Jason W. Chapman, Jason W. Chapman, Jason W. Chapman, Karl R. Wotton   +12 more
doaj   +1 more source

Geolocators reveal migration and pre-breeding behaviour of the critically endangered Balearic Shearwater Puffinus mauretanicus [PDF]

, 2012
Using combined miniature archival light and salt-water immersion loggers, we characterise the year-round individual at-sea movements of Europe’s only critically endangered seabird, the Balearic shearwater Puffinus mauretanicus, for the first time ...
Meier, R, Jones, A., Fayet, A., Guilford, Tim, Guilford, T., Maurice Lou, Fayet, A, Rodríguez Ana, Jones Alice, Jones, Alice, McMinn, Miguel, Rhiannon Meier, Guilford, T, Maurice, L., Rodríguez, A., Guilford, Timothy, Meier, R., Wynn, R, Wynn, Russell, Meier, Rhiannon, Wynn Russell, Rodríguez, A, Ana Rodríguez, Guilford Tim, McMinn, M., Fayet Annette, McMinn Miguel, Meier Rhiannon, McMinn, M, Tim Guilford, Fayet, Annette, Jones, A, Annette Fayet, Rodriguez, Ana, Russell Wynn, Lou Maurice, Miguel McMinn, Maurice, L, Alice Jones, Wynn, R., Maurice, Lou   +40 more
core   +1 more source