Results 51 to 60 of about 488,802 (265)
Mechanisms and Consequences of Partial Migration in Insects
Frontiers in Ecology and Evolution, 2019 Partial migration, where a proportion of a population migrates, while other individuals remain resident, is widespread across most migratory lineages.
Myles H. M. Menz +12 more
doaj +1 more source
White stork movements reveal the ecological connectivity between landfills and different habitats
Movement Ecology, 2023 Background Connections between habitats are key to a full understanding of anthropic impacts on ecosystems. Freshwater habitats are especially biodiverse, yet depend on exchange with terrestrial habitats.
Cosme López-Calderón +8 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Ecology and EvolutionThe Euphrates Softshell Turtle (Rafetus euphraticus) is an endangered freshwater turtle native to the Tigris‐Euphrates river system. Habitat destruction caused by dams and sand mining poses a major threat to the species.
Murat Biricik +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Going, Going, Gone: Is Animal Migration Disappearing
PLoS Biology, 2008 Many of the world's migratory animals are in decline. This essay explores the unique scientific and political challenges of protecting migratory species while they are still common.
Wilcove, David S., Wikelski, Martin
openaire +6 more sources
Introducing a unique animal ID and digital life history museum for wildlife metadata
Methods in Ecology and EvolutionOver the past five decades, a large number of wild animals have been individually identified by various observation systems and/or temporary tracking methods, providing unparalleled insights into their lives over both time and space.
Martin Wikelski +40 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source