Results 161 to 170 of about 27,467,558 (397)

Expression of Wnt pathway mediators in metaplasic tissue in animal model and clinical samples of tendinopathy [PDF]

, 2013
Pauline Po Yee Lui, Yuk Wa Lee, Yin Mei Wong, Xiaoling Zhang, Kerong Dai, Christer Rolf   +5 more
openalex   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Prenatal methotrexate injection increases behaviors possibly associated with depression and/or autism in rat offspring; A new animal model for mental disorder, based on folate metabolism deficit during pregnancy

, 2022
Naoki Amada, Yusuke Kakumoto, Takashi Futamura, Kenji Maeda   +3 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Animal models of hospital-acquired pneumonia: current practices and future perspectives

, 2017
Kenny Bielen, Bart ‘s Jongers, Surbhi Malhotra‐Kumar, Philippe G. Jorens, Herman Goossens, Samir Kumar‐Singh   +5 more
openalex   +1 more source

A SIMPLIFIED BAYESIAN NETWORK MODEL APPLIED IN CROP OR ANIMAL DISEASE DIAGNOSIS [PDF]

, 2009
Helong Yu, Guifen Chen, Dayou Liu
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Gut microbiota regulates serum metabolites in mice with nonalcoholic fatty liver disease via gut metabolites: mechanisms involving branched-chain amino acids and unsaturated fatty acids

Frontiers in Endocrinology
IntroductionIn recent years, nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease globally. Studies indicate that the gut-liver axis plays an important role in the occurrence and development of this disease.
Hao Qiu, Hao Qiu, Yuhang Wen, Yuhang Wen, Yadan Luo, Yadan Luo, Shuya Lv, Shuya Lv, Jingrong Huang, Jingrong Huang, Baoting Chen, Baoting Chen, Ruilin Lu, Ruilin Lu, Lvqin He, Lvqin He, Qian Yang, Qian Yang, Jianhong Han, Jianhong Han, Xuefeng Yan, Xuefeng Yan, Manli He, Manli He, Mingde Zhao, Mingde Zhao, Xiaoxia Zou, Xiaoxia Zou, Congwei Gu, Congwei Gu, Congwei Gu   +30 more
doaj   +1 more source

Animal models [PDF]

Nature, 1987
openaire   +2 more sources