Results 81 to 90 of about 26,422,673 (403)
The crab Neohelice (=Chasmagnathus) granulata: An emergent animal model from emergent countries [PDF]
, 2010 Neohelice granulata (previously known as Chasmagnathus granulata and C. granulatus) is a burrowing semiterrestrial crab found in the intertidal zone of estuaries, salt marshes and mangroves of the South-western Atlantic Ocean. Beginning in the late 1989s,
Spivak, Eduardo Daniel
core +1 more source
Dendritic cells steering antigen and leukocyte traffic in lymph nodes
FEBS Letters, EarlyView.Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta +3 more
wiley +1 more source
Frontiers in ImmunologyIntroductionThe new targeted gene editing technologies, such as the CRISPR/Cas system, enable researchers to insert or delete genes at targeted loci efficiently.
Yang Guo +7 more
doaj +1 more source
Frontiers in Aging Neuroscience, 2016 Postoperative cognitive decline (POCD) is a common complication following anesthesia and surgery, especially in elderly patients; however, the precise mechanisms of POCD remain unclear.
lili qiu +8 more
doaj +1 more source
Respiratory Research, 2022 Background Global distributions and trends of the risk-attributable burdens of chronic obstructive pulmonary disease (COPD) have rarely been systematically explored. To guide the formulation of targeted and accurate strategies for the management of COPD,
Jiahua Zou +14 more
doaj +1 more source
Postnatal maturation of the glomerular filtration rate in conventional growing piglets as potential juvenile animal model for preclinical pharmaceutical research [PDF]
, 2017 Adequate animal models are required to study the preclinical pharmacokinetics (PK), pharmacodynamics (PD) and safety of drugs in the pediatric subpopulation.
Croubels, Siska +8 more
core +3 more sources
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Caspase-1 cleaves PPARγ for potentiating the pro-tumor action of TAMs
Nature Communications, 2017 Tumor associated macrophages (TAMs) promote cancer progression. Here, the author show that caspase-1 promotes TAMs differentiation by attenuating medium-chain acyl-CoA dehydrogenase activity and that inhibition of this axis results in suppression of ...
Zhiyuan Niu +13 more
doaj +1 more source
Animal models of pheochromocytoma.
Histology and histopathology, 2004 Pheochromocytomas are neuroendocrine tumors of adrenal chromaffin cells. They are rare in all species except rats but occur with increased frequency in several human familial tumor syndromes. Concurrence of pheochromocytoma with other tumors sometimes parallels these human syndromes in rats, bovines, horses and dogs but a shared genetic basis for human
Tischler, A.S., Powers, J.F., Alroy, J.
openaire +4 more sources
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source