Results 91 to 100 of about 1,819,816 (315)
Polystyrene microplastics (PS-MPs) are microplastic particles produced during plastic manufacturing and environmental degradation, accumulating over time and entering ecosystems through various pathways, ultimately affecting organisms and inducing toxic ...
Hui-Mei Huang +7 more
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Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Animal models of frailty: current applications in clinical research [PDF]
Alice E Kane,1 Sarah N Hilmer,2–4 John Mach,2–4 Sarah J Mitchell,5 Rafael de Cabo,5 Susan E Howlett1 1Department of Pharmacology, Dalhousie University, Halifax, NS, Canada; 2Kolling Institute of Medical Research and Sydney Medical School ...
Kane AE +5 more
core
Neurodevelopmental animal models of schizophrenia: Effects on prepulse inhibition [PDF]
Epidemiological studies have shown increased incidence of schizophrenia in patients subjected to different forms of pre- or perinatal stress. However, as the onset of schizophrenic illness does not usually occur until adolescence or early adulthood, it ...
Garner, B., Koch, M., van den Buuse, M.
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Cepharanthine hydrochloride: a novel ferroptosis-inducing agent for prostate cancer treatment
BackgroundFerroptosis is an intracellular iron-dependent cell death that is distinct from apoptosis, necrosis, and autophagy. Increasing evidence indicated that ferroptosis plays a crucial role in suppressing tumors, thus providing new opportunities for ...
Jing-Song Guan +9 more
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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Progress towards the development of animal models of chemotherapy-induced gastrointestinal mucositis [PDF]
The pathogenesis of chemotherapy-induced gastrointestinal mucositis is not fully elucidated, which makes it extremely difficult to develop effective interventions.
Min Zhang +7 more
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Functional and mechanistic studies reveal MAGEA3 as a pro-survival factor in pancreatic cancer cells
Background In the era of personalized therapy, functional annotation of less frequent genetic aberrations will be instrumental in adapting effective therapeutic in clinic.
Biswajit Das, Shantibhusan Senapati
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Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Somatic cell nuclear transfer (SCNT) holds great promise for regenerative medicine and agriculture, but its application is severely hampered by low efficiency, primarily attributable to aberrant epigenetic reprogramming.
Shuaipeng Li +5 more
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