Results 71 to 80 of about 1,819,816 (315)

Animal models of soft-tissue sarcoma. [PDF]

open access: yes, 2010
Soft-tissue sarcomas (STSs) are rare mesenchymal tumors that arise from muscle, fat and connective tissue. Currently, over 75 subtypes of STS are recognized.
Kirsch, David G   +5 more
core   +1 more source

Effects of Caffeic Acid Phenethyl Ester on Embryonic Development Through Regulation of Mitochondria and Endoplasmic Reticulum

open access: yesVeterinary Sciences
Caffeic acid phenethyl ester (CAPE) is one of the main active components of the natural medicine propolis, which has antioxidant, anti-tumor, and immunomodulatory activities. This study aimed to analyze the effects and underlying mechanisms of CAPE added
Chu-Man Huang   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Animal models of obsessive–compulsive disorder: utility and limitations [PDF]

open access: yes, 2015
Pino Alonso,1–4 Clara López-Solà,1–3 Eva Real,1–3 Cinto Segalàs,1–3 José Manuel Menchón1–41OCD Clinical and Research Unit, Department of Psychiatry, Hospital de Bellvitge, 2Bellvitge ...
Menchón JM   +4 more
core  

Methyl Paraben Affects Porcine Oocyte Maturation Through Mitochondrial Dysfunction

open access: yesBiomolecules
Parabens are widely used in various industries, which are including chemical, pharmaceutical, food, cosmetic, and plastic processing industries. Among these, methyl paraben (MP) serves as an antimicrobial preservative in processed foods, pharmaceuticals,
Huimei Huang   +5 more
doaj   +1 more source

miR-146a-5p Plays an Oncogenic Role in NSCLC via Suppression of TRAF6

open access: yesFrontiers in Cell and Developmental Biology, 2020
Non-small cell lung cancer (NSCLC) is the most deadly cancer in the world due to its often delayed diagnosis. Identification of biomarkers with high sensitivity, specificity, and accessibility for early detection, such as circulating microRNAs, is ...
Xiangdong Liu   +46 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Informing Involvement around Animal Research [PDF]

open access: yes, 2023
This is the final published version.This report contributes to a growing body of advice around how to involve people affected by health conditions in laboratory or biomedical research.
King, G, Gorman, R, Davies, G
core  

Pharmacokinetics of Repeated Oral Dosing with Coenzyme Q10 in Cavalier King Charles Spaniels with Myxomatous Mitral Valve Disease

open access: yesAntioxidants, 2020
Coenzyme Q10 (Q10) is a mitochondrial cofactor and an antioxidant with the potential to combat oxidative stress in heart failure. This study aims to determine the pharmacokinetics of repeated oral dosing of Q10 in Cavalier King Charles Spaniels (CKCS ...
Liselotte B. Christiansen   +7 more
doaj   +1 more source

Percolation Models and Animals

open access: yesEuropean Journal of Combinatorics, 1996
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

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