Results 51 to 60 of about 1,661,237 (266)

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean   +7 more
wiley   +1 more source

Digestibility of crude nutrients and minerals in C57Bl/6J and CD1 mice fed a pelleted lab rodent diet

open access: yesScientific Reports
In laboratory animals, there is a scarcity of digestibility data under non-experimental conditions. Such data is important as basis to generate nutrient requirements, which contributes to the refinement of husbandry conditions.
Linda F. Böswald   +2 more
doaj   +1 more source

Fisetin reverses the negative effect of Lambda-Cyhalothrin on the maturation process of porcine oocytes in vitro by downregulating GRP78 levels

open access: yesEcotoxicology and Environmental Safety
Lambda-Cyhalothrin (LCT), a potent insecticide, is renowned for its efficacy, rapid onset, and broad-spectrum insecticidal activity. With rising annual demand for LCT, environmental concerns have similarly intensified.
Xiu-wen Yuan   +7 more
doaj   +1 more source

Mapping Childhood Cancer Care Services in Oceania: Methodological Lessons From the SIOP Global Mapping Programme

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT The International Paediatric Oncology Society Global Mapping Programme aims to collect data on global paediatric oncology services by continent, with Africa and Latin America completed. This study reports on the methodology and lessons learned for Oceania, a unique continent with resource disparity across countries, multiple small island ...
Trisha Soosay Raj   +16 more
wiley   +1 more source

Melatonin Alleviates the Damage of Polystyrene Microplastics to Porcine Oocytes by Reducing Oxidative Stress and Mitochondrial Damage, and Regulating Autophagy and Apoptosis Levels

open access: yesAnimals
Polystyrene microplastics (PS-MPs) are microplastic particles produced during plastic manufacturing and environmental degradation, accumulating over time and entering ecosystems through various pathways, ultimately affecting organisms and inducing toxic ...
Hui-Mei Huang   +7 more
doaj   +1 more source

Percolation Models and Animals

open access: yesEuropean Journal of Combinatorics, 1996
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Development and Implementation of a Disease‐Targeted Storybook as a Clinical Tool for Children With Acute Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Although significant progress has been made in childhood leukemia survival, healthcare providers, and caregivers often face challenges in explaining this disease to patients. Disease‐targeted storybooks have been proposed as a tool to facilitate the understanding of diagnoses and treatment.
Nutvipha Ummartyotin   +6 more
wiley   +1 more source

Cepharanthine hydrochloride: a novel ferroptosis-inducing agent for prostate cancer treatment

open access: yesFrontiers in Pharmacology
BackgroundFerroptosis is an intracellular iron-dependent cell death that is distinct from apoptosis, necrosis, and autophagy. Increasing evidence indicated that ferroptosis plays a crucial role in suppressing tumors, thus providing new opportunities for ...
Jing-Song Guan   +9 more
doaj   +1 more source

Animal models of cholangiocarcinoma

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2019
Cholangiocarcinoma (CCA) is an aggressive biliary tract malignancy with a poor overall prognosis. There is a critical need to develop effective targeted therapies for the treatment of this lethal disease. In an effort to address this challenge, preclinical in vivo studies have become paramount in understanding CCA carcinogenesis, progression, and ...
Emilien, Loeuillard   +3 more
openaire   +2 more sources

Animal Models of Hemophilia [PDF]

open access: yes, 2012
The X-linked bleeding disorder hemophilia is caused by mutations in coagulation factor VIII (hemophilia A) or factor IX (hemophilia B). Unless prophylactic treatment is provided, patients with severe disease (less than 1% clotting activity) typically experience frequent spontaneous bleeds.
Denise E, Sabatino   +5 more
openaire   +3 more sources

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