Results 241 to 250 of about 3,105,446 (302)

Animal models for study on rotator cuff healing. [PDF]

World J Orthop
Jiang QL.
europepmc   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Effects of moxibustion therapies on immune function in cancer animal models: a systematic review and meta-analysis. [PDF]

Front Immunol
Liang X, Ma Y, Zhang X, Zhang M, Pan L.
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Animal Models in Rheumatoid Arthritis: Is There a Correlation Between Autoantibodies in Human Pathology and Animal Models? [PDF]

Biology (Basel)
Marco-Bonilla M, Fresnadillo M, de la Riva-Bueno M, Herrero-Beaumont G, Largo R, Mediero A.   +5 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Editorial: Animal models of vascular interventions. [PDF]

Front Cardiovasc Med
Fishbein I, Tulis DA.
europepmc   +1 more source

Self-regulating hydrogel for diabetic wound healing: From animal models to a pilot clinical study. [PDF]

Sci Adv
Zhao L, Chen S, Chen S, Sun Y, Xi L, Huang S, Zhang Y, Dong B, Liao Y, Li J, Qiu J, Liu X.   +11 more
europepmc   +1 more source

Recent advances in methods for establishing animal models of premature ovarian failure. [PDF]

J Ovarian Res
Wang X, Gao X, Li S, Wang R.
europepmc   +1 more source