Results 51 to 60 of about 1,415,177 (267)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Yield Grade and Quality Assessment of Native Buffalo Meat and Beef at Different Ages

Tropical Animal Science Journal, 2020
Boosting meat production potential possibly happens when people will judge meat quality and use their livestock wisely, as they meet up their demand from promising animal like buffalo.
B. K. Roy, N. Huda, K. S. Huque, N. Sultana, N. R. Sarker   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Progesterone-responsive vaginal leiomyoma and hyperprogesteronemia due to ovarian luteoma in an older bitch

BMC Veterinary Research, 2020
Background This is the first report about a vaginal leiomyoma concomitant with an ovarian luteoma in a bitch. Case presentation A 11-year-old intact female Labrador retriever was referred because of anuria, constipation and protrusion of a vaginal mass ...
L. Ferré-Dolcet, S. Romagnoli, T. Banzato, L. Cavicchioli, R. Di Maggio, A. Cattai, M. Berlanda, M. Schrank, A. Mollo   +8 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A Systematic Review of Urban Vegetation Research during 2000–2023: A Bibliometric Analysis

International Journal of Forestry Research
Urban vegetation is a fundamental element and the keystone of urban ecological systems. Therefore, better comprehending the patterns of change over time and space in this vegetation is crucial for more effective urban environment management to enhance ...
Hassan Boukita, Fathalah Elwahab, Mohamed El Ammari, Abdelazziz Chemchaoui, Boutaina Benchahid, Youssef Haouazine, Najiba Brhadda, Rabea Ziri   +7 more
doaj   +1 more source

Factors affecting piglet mortality during the first 24 h after the onset of parturition in large litters: effects of farrowing housing on behaviour of postpartum sows

Animal, 2019
The present study aimed to identify the factors that affect immediate (within 24 h after farrowing onset) postnatal piglet mortality in litters with hyperprolific sows, and investigate their associations with behaviour of postpartum sows in two different
J. Yun, T. Han, S. Björkman, M. Nystén, S. Hasan, A. Valros, C. Oliviero, Y. Kim, O. Peltoniemi   +8 more
doaj   +1 more source

Genetic Diversity of Indonesian Swamp Buffalo Based on Microsatellite Markers

Tropical Animal Science Journal, 2020
Indonesia has high genetic resources of local swamp buffalo with good adaptation across regions. However, these animals decline in both population and genetic quality. This research was conducted to study the genetic diversity of Indonesian swamp buffalo.
F. Saputra, Jakaria Jakaria, A. Anggraeni, C. Sumantri   +3 more
doaj   +1 more source