Results 101 to 110 of about 1,621,199 (300)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

The Ombudsman for Animal Protection

Wrocławsko-Lwowskie Zeszyty Prawnicze
The actual defenders of animal rights in Poland are mainly foundations and associations; the organisation of animal protection is largely grassroots, social and non-governmental. This fact arouses a lot of controversy, mainly because concrete actions are
Hanna Spasowska
doaj   +1 more source

Environment and legal protection of animals in the Republic of Serbia [PDF]

Ekonomika Poljoprivrede (1979), 2018
The aim of this study was to investigate the application of scientific methods of animal protection in the legal legislation of the Republic of Serbia, through assaults on the environment.
Petrović Zdravko, Jović Vojislav, Manojlović Dragan   +2 more
doaj  

The Impact of ‘Selfie’ Tourism on the Behaviour and Welfare of Brown-Throated Three-Toed Sloths

Animals, 2018
The use of wild animals as photo props is prevalent across the globe and is widely recognised to represent a potential animal welfare concern. However, detailed information regarding the specific impacts of such activity on wild animal behaviour is ...
Gemma Carder, Tinka Plese, Fernando Carniel Machado, Suzanne Paterson, Neil Matthews, Laura McAnea, Neil D’Cruze   +6 more
doaj   +1 more source

Policy brief on the organic approach to inputs – Plant protection products, fertilisers, veterinary drugs and feed additives explained [PDF]

, 2019
The plant and animal health care strategy in organic farming strengthensagro-biodiversity, protects the environment as well as animal and human health.
Busacca, Emanuele, Bünemann-König, Else, Gall, Eric, Herforth-Rahmé, Joelle, Lang, Isabella, Magid, Jakob, Maurer, Veronika, Moeskops, Bram, Schmitt, Annegret, Schärer, Hans-Jakob, Speiser, Bernhard, Tamm, Lucius, Walkenhorst, Michael   +12 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

OrgTrace – No Difference in Levels of Bioactive Compounds found in Crops from Selected Organic and Conventional Cultivation Systems [PDF]

, 2011
The objective of the present study was to compare the content of selected bioactive compounds in organically and conventionally grown crops, and to evaluate if the ability of the crops to synthesize selected secondary metabolites was systematically ...
Bysted, Anette, Halekoh, Ulrich, Husted, Søren, Knuthsen, Pia, Laursen, Kristian Holst, Madsen, Katja H, Nielsen , John, Soeltoft, Malene   +7 more
core  

How to be a great dad: Parental care in a flock of greater flamingo (Phoenicopterus roseus) [PDF]

, 2017
In the last years, studies on captive greater flamingos have increased. Research on zoo animals is important to improve the knowledge on these species and to improve their ex-situ and in-situ conservation.
Piccirillo, Alessandra, Regaiolli, Barbara, Sammarini, Carolina, Sandri, Camillo, Spiezio, Caterina, Vallarin, Vittoria   +5 more
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source