Results 51 to 60 of about 607,499 (252)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Illusory or effective? The protection provided by the Romanian authorities to stray dogs [PDF]
Forum Juridic, 2021 The problem that Romania has with stray dogs’ management is well known at national level, but also intensely debated internationally. The main accusation brought against Romania is the authorities’ noncompliance with the principle of minimum suffering ...
Tatiana-Lăcrămioara Șoldănescu
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A historical overview of turkey's animal welfare legislation [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017 There were a number of legal codes which aimed to protect animal welfare in Turkish history, but there was no separate animal welfare law until 2004. Although Animal Protection Law (5199) had been accepted on June 24, 2004, little progress had been shown
Abdullah ÖZEN
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
AnimalsIn recent decades, the exponential growth of the global seafood industry has intensified the exploitation of aquatic invertebrates, particularly decapod crustaceans, whose commercial value continues to rise alongside consumer demand.
Lorenzo Fruscella +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Ethics of Animal Shelters, by Valéry Giroux, Kristin Voigt and Angie Pepper
Canadian Journal of BioethicsIn this review of The Ethics of Animal Shelters, I explore the book’s practical and philosophical approach to ethical dilemmas in animal shelters, such as euthanasia and triage. I highlight the book’s relevance to bioethics, despite the limited explicit
B.V.E. Hyde
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source