Results 51 to 60 of about 631,180 (251)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Jurisprudence and animal protection
Animal Sentience, 2023 Jurisprudence is based on normative principles that go beyond instrumental reasoning and practical goals concerning what is convenient. It concerns justice and truth.
Carlos Montemayor
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Animal Protection: From Property Rights Towards Legal Capacity?
Review of European and Comparative LawThis article examines the evolution of animal protection law from its traditional foundations - anchored in the property-based conception of animals as objects - towards more complex contemporary regulatory models.
István Hoffman, Bernadette Somody
doaj +1 more source
Religious Slaughtering and Organic Labels: Œuvre d'assistance aux bêtes d'abattoirs
European Papers, 2019 (Series Information) European Papers - A Journal on Law and Integration, 2019 4(1), 297-305 | European Forum Insight of 6 May 2019 | (Table of Contents) I. Introduction. - II. Background and facts. - III. Judgment. - IV. Comment. - IV.1.
Lena Hehemann
doaj +1 more source
Illusory or effective? The protection provided by the Romanian authorities to stray dogs [PDF]
Forum Juridic, 2021 The problem that Romania has with stray dogs’ management is well known at national level, but also intensely debated internationally. The main accusation brought against Romania is the authorities’ noncompliance with the principle of minimum suffering ...
Tatiana-Lăcrămioara Șoldănescu
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Proportional Protection of Animals in a Constitutional State
Review of European and Comparative LawAnimal protection in the modern (model) constitutional state constitutes a complex constitutional issue that essentially boils down to the necessity of applying the constitutional mechanism of proportionality to this subject matter.
Wojciech Mojski
doaj +1 more source
A historical overview of turkey's animal welfare legislation [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017 There were a number of legal codes which aimed to protect animal welfare in Turkish history, but there was no separate animal welfare law until 2004. Although Animal Protection Law (5199) had been accepted on June 24, 2004, little progress had been shown
Abdullah ÖZEN
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source