Results 61 to 70 of about 638,332 (291)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

LEGAL PROTECTION OF ANIMALS IN IRAN: FROM THE AVESTA TO THE BILL ON PROTECTION OF ANIMALS

open access: yesТеория государства и права, 2021
Авторы рассматривают проблемы правового регулирования защиты животных в современной Республике Иран, опираясь на данные, представленные организацией «Всемирная защита животных». В статье исследуются традиции обращения с животными, присущие иранцам в древний период их истории.
openaire   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The effects of level of support for animal protection organisations on attitudes to the use of animals and other social issues

open access: yes, 2012
Animal protection issues are being advanced increasingly by Non-Government Organisations, yet the views of their supporters are little understood. We surveyed attitudes towards animals and other social issues in 3,462 university students from over 103 ...
Izmirli, S.   +3 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The Ethics of Animal Shelters, by Valéry Giroux, Kristin Voigt and Angie Pepper

open access: yesCanadian Journal of Bioethics
In this review of The Ethics of Animal Shelters, I explore the book’s practical and philosophical approach to ethical dilemmas in animal shelters, such as euthanasia and triage. I highlight the book’s relevance to bioethics, despite the limited explicit
B.V.E. Hyde
doaj   +1 more source

A socio-economic survey of pangolin hunting in Assam, Northeast India [PDF]

open access: yesNature Conservation, 2018
India has been identified as a source country for the illegal international trade in endangered pangolins, “scaly mammalian anteaters”, widely considered as the “world’s most trafficked mammal”.
Neil D’Cruze   +4 more
doaj   +3 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

CITES and Animal Welfare: The Legal Void for Individual Animal Protection

open access: yes, 2021
The protection of individual animal welfare is a matter of global concern meriting regulation under international law. Current international instruments intending to regulate animals offer piecemeal, incidental and ad-hoc protection for individual animal
Nyilas, Francesca
core  

Home - About - Disclaimer - Privacy