Results 61 to 70 of about 1,622,799 (297)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A historical overview of turkey's animal welfare legislation [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017 There were a number of legal codes which aimed to protect animal welfare in Turkish history, but there was no separate animal welfare law until 2004. Although Animal Protection Law (5199) had been accepted on June 24, 2004, little progress had been shown
Abdullah ÖZEN
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cooperation in manure-based biogas production networks: An agent-based modeling approach [PDF]
, 2018 Biogas production from manure has been proposed as a partial solution to energy and environmental concerns. However, manure markets face distortions caused by considerable unbalance between supply and demand and environmental regulations imposed for soil
Fraccascia, Luca +3 more
core +4 more sources
BENCHMARKING OF ANTIBODY TITRES SELECTIONS USING THE RANKING METHOD
Ветеринарная патология, 2022 Based on the serological monitoring results the humoral immunity level in birds was assessed after the use of three variants of inactivated vaccines against avian influenza, which causative agent is capable of genetic rearrangements and generation of ...
V. Yu. Kulakov +3 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Novel treatment strategies for chronic kidney disease: insights from the animal kingdom [PDF]
, 2018 Many of the >2 million animal species that inhabit Earth have developed survival mechanisms that aid in the prevention of obesity, kidney disease, starvation, dehydration and vascular ageing; however, some animals remain susceptible to these ...
Arnold, Walter +7 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A socio-economic survey of pangolin hunting in Assam, Northeast India [PDF]
Nature Conservation, 2018 India has been identified as a source country for the illegal international trade in endangered pangolins, “scaly mammalian anteaters”, widely considered as the “world’s most trafficked mammal”.
Neil D’Cruze +4 more
doaj +3 more sources