Results 41 to 50 of about 238,313 (296)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Speaking Theologically of Animal Rights

open access: yesJournal of Moral Theology, 2014
Is moral agency necessary (or constitutive of) moral standing/rights? This essay argues no, particularly with regard to non-human animals, who deserve both moral rights and to be ascribed moral patient status.
James E. Helmer
doaj  

Breaking the Silence about the Animals We Eat

open access: yesBarnboken: Tidskrift för Barnlitteraturforskning, 2021
Some 77 billion terrestrial animals are reared for human consumption globally every year. The moral implications of killing animals for food and the material conditions of these animals in intensive animal agriculture have seldom been discussed in ...
Marianna Koljonen
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Animal rights & human identity: a polemical quest for authenticity [PDF]

open access: yes, 2000
This thesis examines the hypothesis that The conflict between animal advocates and animal users is far more than a matter of contrasting tastes or interests.
O'Neill, Pamela Susan   +1 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

If Rivers Have Rights, do Fish Have Rights Too? Examining the Relationship Between Rights of Nature and Animal Rights

open access: yesJournal of Animal Law, Ethics and One Health
This article examines the intersection of the Rights of Nature (RoN) and animal rights, two increasingly influential paradigms in both academic discourse and judicial practice.
Eva Bernet Kempers
doaj   +1 more source

The political approach of animal rights from the perspective of the rights theory

open access: yesRevista Iberoamericana de Bioética, 2017
Traditionally, discussions about animal rights have focused on defending, in different ways, abolitionist or regulatory approaches. Recently, there has been a political change in the way of understanding these rights, which fits better a legal approach ...
José Luis Rey Pérez
doaj   +1 more source

Misunderstanding Familiar Objects in an Imagined Future: A Critical Method for Discovery

open access: yesOn_Culture, 2023
The location and presentation of an object establish layered narratives about the object, which habit and familiarity protect. This shield obscures an object’s effects on people and places that originate in that object’s materials and manufacturing ...
Kiersten Thamm
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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