Results 51 to 60 of about 3,830,706 (291)

Il dilemma etico dei pet. Tra bestie, animali e persone

open access: yesRelations, 2022
The main aim of this paper is to demonstrate the need to discuss the moral status of pets, showing how this can even offer an opportunity to rethink the entire set of relationships between humans and non-human nature.
Matteo Andreozzi
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The political approach of animal rights from the perspective of the rights theory

open access: yesRevista Iberoamericana de Bioética, 2017
Traditionally, discussions about animal rights have focused on defending, in different ways, abolitionist or regulatory approaches. Recently, there has been a political change in the way of understanding these rights, which fits better a legal approach ...
José Luis Rey Pérez
doaj   +1 more source

Animal rights, animal minds, and human mindreading [PDF]

open access: yesJournal of Medical Ethics, 2006
Do non-human animals have rights? The answer to this question depends on whether animals have morally relevant mental properties. Mindreading is the human activity of ascribing mental states to other organisms. Current knowledge about the evolution and cognitive structure of mindreading indicates that human ascriptions of mental states to non-human ...
Mameli G, Bortolotti L
openaire   +3 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Human vs. Animal Rights: In Defense of Animal Research

open access: yes, 1989
Members of the American Medical Association's Group on Science and Technology present a condensation of the AMA's 1989 White Paper on Animal Research. Among the topics covered are the history of scientific research with animals, philosophical challenges
Smith, Steven J.   +4 more
core   +1 more source

Towards Legal Protection of Animal Interests: Nature-Based or Sentience-Based Approach to Animal Rights

open access: yesJournal of Animal Law, Ethics and One Health
This article examines the idea of animal rights, arguing for a sentience-based or interest-based approach, rather than a nature-based approach. It begins by exploring the philosophical foundations of animal rights, addressing the question of whether ...
Zorana S. Todorović
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Animal rights & human identity: a polemical quest for authenticity [PDF]

open access: yes, 2000
This thesis examines the hypothesis that The conflict between animal advocates and animal users is far more than a matter of contrasting tastes or interests.
O'Neill, Pamela Susan   +1 more
core  

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