Results 71 to 80 of about 221,282 (257)

The Problem of Animal Rights in Selected Works by Dorota Probucka

open access: yesStudia Ecologiae et Bioethicae
This article presents the idea of animal rights as perceived by a Polish philosopher and ethicist, Dorota Probucka. It is divided into three sections that delve into the development and significance of animal rights from the perspectives of both ...
Joanna Glensk
doaj   +1 more source

The Role of Neuterization in The Welfare of Urban Animals, Comparative Study of Iran, Europe, Latin America [PDF]

open access: yesپژوهشنامه حقوق تطبیقی
Some ethicists believe that the philosophy of animal rights considers the sterilization/neuterization of animals as a violation of the principle of respect for them, and therefore Trap-Neuter Return (TNR) programs are also impermissible. Because it seems
Shima Arab Asadi, Nafise Maktabi
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Cultivating a Value for Non-Human Interests through the Convergence of Animal Welfare, Animal Rights, and Deep Ecology in Environmental Education

open access: yesEducation Sciences, 2015
While the original objective of environmental education (EE) and education for sustainable development (ESD) acquired an awareness of the natural world and its current plight, animal welfare (AW), animal rights (AR), and deep ecology (DE) have often been
Helen Kopnina, Brett Cherniak
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Application of 3R principles in small animal GLP testing of biomaterials

open access: yesCurrent Directions in Biomedical Engineering, 2019
On the protection of animals used for scientific purposes, the EU Parliament adopted Directive 2010/63/EU. The essential factor is the 3R principle: Replacement, Reduction and Refinement.
Kischkel Sabine   +5 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

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