Results 81 to 90 of about 5,350,274 (343)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Is There a Need for a More Expansive Use of Ethics and Values in Reflecting on the Use of Animals in Scientific Research?

open access: yesAnimals, 2014
Although reflecting a long tradition of moral reflection that the use of animals is acceptable as long as it is humane, the tension between causing harm to animals in research and the benefits to humans can nevertheless be troubling.
Mark W. Fisher
doaj   +1 more source

Explaining Support for Animal Rights: A Comparison of Two Recent Approaches to Humans, Nonhuman Animals, and Postmodernity [PDF]

open access: yes, 2001
Questions on "animal rights" in a cross-national survey conducted in 1993 provide an opportunity to compare the applicability to this issue of two theories of the socio-political changes summed up in "postmodernity": Inglehart's (1997) thesis of ...
Franklin, Adrian   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Categorical Imperative in Defence of Animal Rights. Christine Korsgaard’s Ethical Extensionism

open access: yesEthics in Progress, 2018
In this paper, I present Christine Korsgaard’s style of building a conception of animal rights protection based on a concept of Kantian provenance, namely “end in itself”.
Małgorzata Adamska
doaj   +1 more source

Expanding Global Justice: The International Protection of Animals [PDF]

open access: yes, 2013
This article examines and rejects the view that nonhuman animals cannot be recipients of justice, and argues that the main reasons in favor of universal human rights and global justice also apply in the case of the international protection of the ...
Horta, Oscar
core  

Animal Agriculture Laws on the Chopping Block: Comparing United States and Brazil [PDF]

open access: yes, 2014
Brazil and the United States are among the largest producers and exporters of livestock in the world. This raises important animal rights and environmental concerns. While many of the impacts of industrial animal agriculture are similar in Brazil and the
Bennett, Elizabeth
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Pressure politics: a politics of collective consumption? [PDF]

open access: yes, 2005
The nature of a politics of collective consumption is reviewed in terms of how we can distinguish those actions that pursue a broader public interest.
Grant, Wyn
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy