Results 111 to 120 of about 9,809,915 (420)
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner+7 more
wiley +1 more source
Rendering-as-a-Service: Taxonomy and Comparison [PDF]
The movies like the Avatar are a good example of the stunning visual effects that the animation could bring into a movie.The 3D wire frame models are converted to 3D photo realistic images using a process called the rendering. This rendering process is offered as a service in the cloud, where the animation files to be rendered are split into frames and
arxiv
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Science and Faith; Or, Man as an Animal and Man as a Member of Society. Paul Topinard , Thomas J. McCormack [PDF]
Wendell Thomas
openalex +1 more source
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Scientometric Analysis: An Emerging Tool in Veterinary and Animal Scientific Research
The present study is an evaluation of published papers in the field of scientometrics–bibliometrics in veterinary or animal studies. The objective was the quantitative evaluation of the scientific content and the bibliometric details of papers that had ...
Georgia A. Vaitsi+6 more
doaj +1 more source
IUMENTA: A generic framework for animal digital twins within the Open Digital Twin Platform [PDF]
IUMENTA (Latin for livestock) is an innovative software framework designed to construct and simulate digital twins of animals. By leveraging the powerful capability of the Open Digital Twin Platform (ODTP) alongside advanced software sensors, IUMENTA offers researchers a user-friendly tool to seamlessly develop adaptive digital replicas of animal-based
arxiv
GRAVITAS: Portraits of a Universe in Motion [PDF]
GRAVITAS is a self-published DVD that presents a visual and musical celebration of the beauty in a dynamic universe driven by gravity. Animations from supercomputer simulations of forming galaxies, star clusters, galaxy clusters, and galaxy interactions are presented as moving portraits of cosmic evolution.
arxiv
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang+2 more
wiley +1 more source
Traffic noise inhibits inhibitory control in wild-caught songbirds
Summary: Anthropogenic noise is ubiquitous across environments and can have negative effects on animals, ranging from physiology to community structure.
Christopher N. Templeton+4 more
doaj