Results 141 to 150 of about 3,681,506 (310)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Building a Culture of Care in Laboratory Animal Science through practicing "remembrance": A reflection on local practices in Sri Lanka. [PDF]

open access: yesAnimal Model Exp Med
Amarasekara ADDS   +5 more
europepmc   +1 more source

Worldwide Research Trends for Chelates in Animal Science: A Bibliometric Analysis. [PDF]

open access: yesAnimals (Basel), 2023
Ghassemi Nejad J   +5 more
europepmc   +1 more source

表紙・目次 [PDF]

open access: yes, 1986
Okayama Association for Laboratory Animal Science,
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

裏表紙・英文目次 [PDF]

open access: yes, 2006
Okayama Association for Laboratory Animal Science,
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The role of extracellular vesicles in murine asthma model: insights into IgE-independent mast cell activation within animal science. [PDF]

open access: yesJ Anim Sci Technol
Kim HW   +13 more
europepmc   +1 more source

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