Results 41 to 50 of about 1,384,360 (264)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Follistatin controls the number of murine teeth by limiting TGF-β signaling

iScience
Summary: Supernumerary teeth are common developmental anomalies of dentition. However, the factors and mechanisms driving their formation remain largely unknown.
Shicheng Zhu, Suman Huo, Zhongzheng Wang, Caiyan Huang, Chuanxu Li, Hanjing Song, Xueqin Yang, Rui He, Cheng Ding, Mengsheng Qiu, Xiao-Jing Zhu   +10 more
doaj   +1 more source

Animism and Science

Religions, 2023
I discuss whether animism, the worldview that (some) objects, plants and animals are capable of communication, rational reflection and intentional action, is in conflict with contemporary science. I distinguish two conflicts. The first points to conflicting claims regarding the abilities of objects, plants and animals made by scientists and animists ...
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Regulation of interstitial fluid flow in adventitia along vasculature by heartbeat and respiration

iScience
Summary: Converging studies showed interstitial fluid (ISF) adjacent to blood vessels flows in adventitia along vasculature into heart and lungs. We aim to reveal circulatory pathways and regulatory mechanism of such adventitial ISF flow in rat model. By
Hongyi Li, Bei Li, Wenqi Luo, Xi Qi, You Hao, Chaozhi Yang, Wenqing Li, Jiazheng Li, Zhen Hua, Tan Guo, Zhijian Zheng, Xue Yu, Lei Liu, Jianping Zhao, Tiantian Li, Dahai Huang, Jun Hu, Zongmin Li, Fang Wang, Hua Li, Chao Ma, Fusui Ji   +21 more
doaj   +1 more source

Future Portrait of the Athletic Brain: Mechanistic Understanding of Human Sport Performance Via Animal Neurophysiology of Motor Behavior

Frontiers in Systems Neuroscience, 2020
Sport performances are often showcases of skilled motor control. Efforts to understand the neural processes subserving such movements may teach us about general principles of behavior, similarly to how studies on neurological patients have guided early ...
Eros Quarta, Erez James Cohen, Riccardo Bravi, Diego Minciacchi   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Long-term intermittent hypoxia in mice induces inflammatory pathways implicated in sleep apnea and steatohepatitis in humans

iScience
Summary: Obstructive sleep apnea (OSA) induces intermittent hypoxia (IH), an independent risk factor for non-alcoholic fatty liver disease (NAFLD). While the molecular links between IH and NAFLD progression are unclear, immune cell-driven inflammation ...
Jonathan Gaucher, Emilie Montellier, Guillaume Vial, Florent Chuffart, Maëlle Guellerin, Sophie Bouyon, Emeline Lemarie, Yoshiki Yamaryo Botté, Aya Dirani, Raoua Ben Messaoud, Marie Joyeux Faure, Diane Godin Ribuot, Charlotte Costentin, Renaud Tamisier, Cyrille Y. Botté, Saadi Khochbin, Sophie Rousseaux, Jean-Louis Pépin   +17 more
doaj   +1 more source