Results 51 to 60 of about 14,140,164 (295)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A Bibliometric Study of the Publication Patterns of Scientists in South Africa 1992-96
A bibliometric study of the publication patterns of a selected group of academic and research scientists of ten universities of South Africa for a period of five years, 1992-96.
Daisy Jacobs
doaj
Summary: The One Health (OH) approach, integrating aspects of human, animal, and environmental health, still lacks robustly quantified insights into its complex relationships.
Ya Tian +11 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Animal Science Newsletter, Spring 2011 [PDF]
Dedicated to the Alumni and Friends of the Animal Sciences Department, University of ...
University of Arkansas, Fayetteville. Department of Animal Sciences
core +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Sheep are sentient, but not identical
Marino & Merskin (M&M) provide a timely reminder that sheep have advanced cognitive abilities, but do we still have to provide evidence to justify animal sentience? In the EU, regulations are designed to support farm animal welfare.
Alison Hanlon
doaj +1 more source
Glutamine in Animal Science and Production [PDF]
With its many proposed metabolic roles, glutamine would seem to have major potential in normal animal production systems as well as during situations involving adverse challenges. In practice, however, responses to glutamine supplementation have been inconsistent. Thus, during lactation and growth studies in ruminants, both positive and null effects on
G E, Lobley, S O, Hoskin, C J, McNeil
openaire +2 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

