Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Progressive trends on the application of artificial neural networks in animal sciences - A review. [PDF]
Vet Med (Praha), 2022 Bauer EA.
europepmc +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Our endeavor to write a new chapter in the development of laboratory animal sciences. [PDF]
Animal Model Exp Med, 2022 Jiang JD.
europepmc +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
MENGINTEGRASIKAN PSIKOLOGI MELALUI PERUMUSAN KEMBALI DOMAIN OBYEK STUDI
Buletin Psikologi, 2015 Psychology has been in the past and now is a fragmented science. One reason of the fragmentation is a disagreement about the subject matter of psychology. This paper attempts to review in detail the state of the subject matter disagreement. Analogy from
Magda Bhinnety
doaj +1 more source
The 1st online academic salon on monkeypox virus by Chinese Association for Laboratory Animal Sciences (2022, June 10th, Beijing, China). [PDF]
Animal Model Exp Med, 2022 AMEM Editorial Office.
europepmc +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
ASAS-NANP symposium: mathematical modeling in animal nutrition: limitations and potential next steps for modeling and modelers in the animal sciences. [PDF]
J Anim Sci, 2022 Jacobs M +6 more
europepmc +1 more source