Results 71 to 80 of about 1,384,360 (264)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Cutting-Edge Topics in Research on Veterinary Sciences

open access: yesSVU-International Journal of Veterinary Sciences, 2018
We are pleased to announce the first edition of the SVU-International Journal of Veterinary Sciences (SVU-IJVS). We hope that this journal will advance the field of animal sciences and related biomedical disciplines.
Seddik Hammad   +2 more
doaj  

Florida Dairy Farm Situation and Outlook 2003

open access: yesEDIS, 2003
This document is AN138, one of a series of the Department of Animal Sciences, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Published February 2003.
Russ Giesy   +5 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Automatic imitation of intransitive actions in macaws

open access: yesiScience
Summary: Automatic imitation is the involuntary tendency of humans to copy others’ actions even when counterproductive. We examined the automatic imitation of intransitive actions in blue-throated macaws (Ara glaucogularis), employing a stimulus-response-
Esha Haldar   +2 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Can Myofascial Trigger Points Involve Nociplastic Pain? A Scoping Review on Animal Models

open access: yesJournal of Pain Research, 2023
Wiktoria Matuska,1 Jakub Matuska,2 Elżbieta Skorupska,2 Maria Siwek,3 Pablo Herrero,4 Manel M Santafé5 1Faculty of Veterinary Medicine and Animal Science, University of Life Sciences, Poznań, Poland; 2Department of Physiotherapy, University ...
Matuska W   +5 more
doaj  

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