Results 141 to 150 of about 809,866 (309)

Novel computational models offer alternatives to animal testing for assessing eye irritation and corrosion potential of chemicals. [PDF]

Artif Intell Life Sci, 2021
Silva AC, Borba JVVB, Alves VM, Hall SUS, Furnham N, Kleinstreuer N, Muratov E, Tropsha A, Andrade CH.   +8 more
europepmc   +1 more source

animal soup sample data and ground truth data for tests

, 2023
Caitlin Lewis
openalex   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Kidney Organoid and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing. [PDF]

Front Pharmacol, 2021
Chen WY, Evangelista EA, Yang J, Kelly EJ, Yeung CK.   +4 more
europepmc   +1 more source

Evidence of SARS-CoV-2 infection in companion animals from owners who tested positive for COVID-19 in the Valley of Mexico [PDF]

Edith A. Fernández-Figueroa, Deborah V. Espinosa-Martínez, Haydee Miranda-Ortíz, Erika Ruíz‐García, Juan M. Figueroa-Esquivel, Miriam L. Becerril-Moctezuma, Anallely Muñoz-Rivas, César A. Ríos-Muñóz   +7 more
openalex   +1 more source

The statistical power analysis of tests used in animal breeding studies on lamb birth weight in Turkey [PDF]

, 2008
İsmet DOĞAN, Nurhan DOĞAN
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

The FDA's plan to phase out animal testing. [PDF]

Trends Biotechnol
Gerke S, Balamut J, Wagner JK.
europepmc   +1 more source

Studies on the Establishment of the Testing Methods on Bioconcentration of Hazardous Chemicals by Marine Fish Species-I. Applicability of Marine Fish Species as an Experimental Animal for a Testing Method on Bioconcentration of Hazardous Chemicals.

, 1995
Hisashi Yamada, Kazufumi Takayanagi
openalex   +2 more sources