Results 171 to 180 of about 282,052 (348)
Alternatives for Animal Testing: A More Humane Approach To Clinical Research
, 2023 Santosh Kumar +2 more
openalex +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Current Strategies in Assessment of Nanotoxicity: Alternatives to In Vivo Animal Testing [PDF]
, 2021 Hung-Jin Huang +5 more
openalex +1 more source
Consumer Willingness to Pay for Livestock Credence Attribute Claim Verification [PDF]
A choice experiment was used to determine consumer value for verification of livestock production process attributes. Willingness to pay for verification of production process attributes varied for both milk and pork chops across attributes and verifying
Olynk, Nicole J. +2 more
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
An Ontology To Represent Knowledge On Animal Testing Alternatives [PDF]
, 2009 Thomas Wächter +6 more
openalex +1 more source
Human skin equivalent as an alternative to animal testing.
GMS Krankenhaushygiene interdisziplinar, 2008 The 3-D skin equivalent can be viewed as physiologically comparable to the natural skin and therefore is a suitable alternative for animal testing. This highly differentiated in vitro human skin equivalent is used to assess the efficacy and mode of action of novel agents.
Mertsching, H +3 more
openaire +2 more sources
Valuing Animal Welfare with Choice Experiments: An Application to Swedish Pig Production [PDF]
In this paper, the demand for animal welfare attributes when buying pork fillet is investigated among Swedish respondents. More specifically, the coefficients of an indirect utility function and willingness to pay for animal welfare attributes are ...
Liljenstolpe, Carolina
core +1 more source