Results 211 to 220 of about 282,052 (348)

Ganglioside Binding Assay: A Complementary Approach for Enhanced Tetanus Toxoid Quality Control. [PDF]

Toxins (Basel)
Tanoue Y, Shitada C, Nakamichi M, Nakamichi N, Sakamoto C, Kim H, Kumeda K, Ochiai M, Yamaori S, Senoh M, Takahashi M.   +10 more
europepmc   +1 more source

Finding opportunities in the area of Alternative Methods to Animal Testing for Romania and inauguration of the Romanian Center for Alternative Test Methods (ROCAM)

, 2015
Lucian Farcal
openalex   +2 more sources

Toxicity tests in animals: alternative models.

Environmental Health Perspectives, 1993
openaire   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Navigating complexity in modern toxicology: the role of omics in short-term in vivo studies. [PDF]

Toxicol Sci
Mitchell CA, Wehmas L, Rouquié D, Caiment F, Currie RA, Crute CE.   +5 more
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Revision of the Choices Nutrient Profiling System. [PDF]

Nutrients
Smorenburg H, Kissock KR, Beck EJ, Mathur P, Hamaker B, Lissner L, Marostica MR, Nnam N, Takimoto H, Roodenburg AJC.   +9 more
europepmc   +1 more source

China is Taking Steps toward Alternatives to Animal Testing [PDF]

, 2012
Rodger Curren, Brian Jones
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Perspective of using <i>in vitro</i> models to understand immunotherapy-induced cytokine release syndrome. [PDF]

Front Immunol
Perkins E, Cooper C, Lund E, Alb M, Morgan H, Fogal B, Hewitt P, Mazein A, Ostaszewski M, Sewald K.   +9 more
europepmc   +1 more source