Results 51 to 60 of about 222,512 (339)

Scientific Opinion on the Role of Tick Vectors in the Epidemiology of Crimean-Congo Hemorrhagic Fever and African Swine Fever in Eurasia [PDF]

open access: yesEFSA Journal, 2010
The report provides an update on the role of the tick vectors in the epidemiology of African swine fever (ASF) and Crimean and Congo haemorrhagic fever (CCHF) in Eurasia, specifically to review of the geographical distribution of the relevant ticks with ...
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Scientific Opinion on Hatchery Waste as animal by‐products

open access: yesEFSA Journal, 2011
The risk posed by the possible use of dead‐in‐shell chicks for the production of processed petfood was assessed. According to current legislation two processing methods were considered i) treatment to a minimum Fc value of 3; and ii) treatment of at ...
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Scientific Opinion on the electrical parameters for the stunning of lambs and kid goats [PDF]

open access: yesEFSA Journal, 2013
The Panel on Animal Health and Welfare was asked to deliver a scientific opinion on two studies performed by IRTA: “Evaluation of the electrical stunning effectiveness in sheep with a current intensity lower than 1 Ampere” and “Evaluation of the ...
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Statistical Review of Animal trials -- A Guideline [PDF]

open access: yesarXiv, 2021
Examinations of any experiment involving living organisms require justifications of the need and moral defensibleness of the study. Statistical planning, design and sample size calculation of the experiment are no less important review criteria than general medical and ethical points to consider.
arxiv  

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Scientific Opinion on electrical requirements for poultry waterbath stunning equipment [PDF]

open access: yesEFSA Journal, 2014
The European Commission (EC) requested that the EFSA Panel on Animal Health and Welfare (AHAW Panel) delivers a scientific opinion on a study that proposes parameters for poultry electrical waterbath stunning different to those laid down in Council ...
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Positive Wild Animal Welfare

open access: yesBiology & Philosophy, 2023
AbstractWith increasing attention given to wild animal welfare and ethics, it has become common to depict animals in the wild as existing in a state dominated by suffering. This assumption is now taken on board by many and frames much of the current discussion; but needs a more critical assessment, both theoretically and empirically.
Browning, Heather, Veit, Walter
openaire   +5 more sources

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

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