Results 51 to 60 of about 744,936 (304)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Statement on the use of animal‐based measures to assess the welfare of animals
EFSA Journal, 2012 The overall aim of the work outlined in this statement is to help establish a common framework for future scientific opinions dealing with the use of animal‐based measures to assess the welfare of animals.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Scientific Opinion on Rift Valley fever [PDF]
EFSA Journal, 2013 Based on a comprehensive review of literature and OIE (World Animal Health Organisation) outbreak reports, this scientific opinion reports, first, that there is no evidence that Rift Valley fever (RVF) has spread to previously uninfected countries during
EFSA Panel on Animal Health and Welfare (AHAW)
doaj +1 more source
Farm-Animal Welfare, Legislation, and Trade [PDF]
, 2007 The US has among the weakest farm-animal-welfare standards in the developed world. Although improvements in farm-animal welfare are economically feasible, nations and states enacting protective regulation are threatened by competition with cheaper, non ...
Leahy, Cheryl, Matheny, Gaverick
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Scientific Opinion on the risk of entry of Aethina tumida and Tropilaelaps spp. in the EU [PDF]
EFSA Journal, 2013 Small hive beetle (SHB) and Tropilaelaps are bee diseases considered exotic in the EU. SHBis a flying coleopteran that can be attracted to the odours of bees and bee products.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj +1 more source
Don\u27t Be Cruel (Anymore): A Look at the Animal Cruelty Regimes of the United States and Brazil with A Call for A New Animal Welfare Agency [PDF]
, 2016 In the United States and around the world, animals exploited for human use suffer cruel and needless harm. The group bearing the brunt of this exploitation--agricultural animals--is routinely exempted from the largely ineffective and rarely enforced ...
Cassuto, David N
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Scientific Opinion on monitoring procedures at slaughterhouses for pigs
EFSA Journal, 2013 This scientific opinion proposes toolboxes of welfare indicators for developing monitoring procedures at slaughterhouses for pigs stunned with the head‐only electrical method or carbon dioxide at high concentration.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj +1 more source