Results 81 to 90 of about 3,566 (282)
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja +8 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Benson Tong. Unsubmissive Women: Chinese Prostitutes in Nineteenth Century San Francisco. Norman and London: University of Oklahoma Press, 1994. xix, 203 pp. Hardcover $24.95, isbn 0-8061-2653-1. [PDF]
, 1996 Book reviewIn lieu of an abstract, here is a brief excerpt of the content: Notes 1. Making Waves: An Anthology of Writings by and about Asian American Women is a collection of essays edited by Asian Women United of California, and published by ...
Joe Laidler, KA
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Animalistic Images in Prose by E. Canetti and А. P. Platonov
Научный диалог, 2017 Animalistic images in the prose of the Austrian writer, Nobel prize winner Elias Canetti (1905-1994) and the Russian writer A. P. Platonov (1899-1951) are discussed.
E. M. Shastina, N. E. Seybel
doaj
Ekoantropologia antyhumanistyczna. Przypadek Johna Nicholasa Graya
Studia Ecologiae et Bioethicae, 2015 Antihumanistic eco-anthropology. The case of John Nicholas Gray This article presents an outline of John Nicholas Gray’s position on the humanistic paradigm in the philosophical anthropology and ethics taken from a radically environmental perspective. It
Piotr Domeracki
doaj +1 more source
Reconsidering a transplant: A response to Wagner [PDF]
, 2016 Nils-Frederic Wagner takes issue with my argument that influential critics of “transplant” thought experiments make two cardinal mistakes. He responds that the mistakes I identify are not mistakes at all.
Beck, Simon
core +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source