Results 111 to 120 of about 473,768 (340)
Sillages Critiques, 2016 The article examines Simon Stephens's seminal play Three Kingdoms (2012), a defining moment in his enduring working relationship with director Sebastian Nübling and a decidedly internationalist staging effort that enabled cross-collaboration between ...
Vicky Angelaki
doaj +1 more source
On Muzzles and Faces: The Semiotic Limits of Visage and Personhood. [PDF]
Int J Semiot Law, 2022 Leone M.
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Artifacting Identity. How Grillz, Ball Gags and Gas Masks Expand the Face. [PDF]
Topoi (Dordr), 2022 Voto C, Soro E.
europepmc +1 more source
Environmental Humanities: Voices from the Anthropocene by Serpil Oppermann and Serenella Iovino [PDF]
, 2018 Review of Environmental Humanities: Voices from the Anthropocene by Serpil Oppermann and Serenella Iovino ...
Banting, Pamela
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
China culls wild animals to prevent new SARS threat [PDF]
, 2004 Jonathan Watts
openalex +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source