Results 101 to 110 of about 2,912 (306)
Animality in British Romanticism The Aesthetics of Species
The scientific, political, and industrial revolutions of the Romantic period transformed the status of humans and redefined the concept of species. This book examines literary representations of human and non-human animality in British Romanticism.
Heymans, Peter.
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Capturing Animality: An Evolutionary Approach to Animal Attitudes
, 2018 The purpose of the series of five studies presented in this dissertation is to shed new light on how our long history of interactions with animals has led to the evolution of psychological adaptations structuring our attitudes about animal—that comprise ...
Steklis, Netzin Gerald
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Differentiating Animality from Agency. Towards a Foundation for Cognition
, 2008 The notion of cognition has been difficult to pin down. Embodied and situated approaches to cognition now suggests that agency, construed in terms of perceptionaction coupling, might provide a clear foundation for cognition.
Keijzer, F.A.,
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
On Muzzles and Faces: The Semiotic Limits of Visage and Personhood. [PDF]
Int J Semiot Law, 2022 Leone M.
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The recognizable face of fear: Domestication and redemption of the animal monster in The Exorcist
Gragoatá, 2013 This article analyses the function of animal traits in the transformation from human to monster in the movie “The Exorcist”, based on the homonymous best-seller by William Peter Blatty.
Marcia Heloisa Amarante Gonçalves
doaj
Artifacting Identity. How Grillz, Ball Gags and Gas Masks Expand the Face. [PDF]
Topoi (Dordr), 2022 Voto C, Soro E.
europepmc +1 more source