Results 111 to 120 of about 2,912 (306)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Social Sciences in One Health: Insights From Multiple Worlds Perspectives on the Dam Rupture in Brumadinho-Brazil. [PDF]
Front Public Health, 2021 Brandão APD +4 more
europepmc +1 more source
Can Flush count?: Virginia Woolf, animality and numbers
, 2023 ‘Can Flush Count?’ The short answer is ‘Yes – But, in more ways than one!’ This essay counts some of the ways. The historical, lived dog, Flush (c.1840-1854), companion of the poet Elizabeth Barrett Browning, given to her by Mary Russell Mitford, and the
Goldman, Jane
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Animal agency, animal awareness and animal welfare
Animal Welfare, 2019 AbstractIn nature, animals need to actively engage with the environment in order to prosper in survival and reproduction. Hence, agency is a central adaptive characteristic of animal life. In this paper, I propose that from the adaptive/functional point of view, four levels of agency can be distinguished, namely passive/reactive agency (animal being ...
openaire +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
(Des)troçosThe article proposes a reading of Giorgio Agamben’s La voce umana (The human voice, 2023) in the context of the development of his philosophy of language, and focuses in particular on the consequences of his theory of the “voice” for his definition of ...
Carlo Salzani, Ermanno Castanò
doaj +1 more source
Physical Review EHere we introduce simple structures for the analysis of complex hypergraphs, hypergraph animals. These structures are designed to describe the local node neighbourhoods of nodes in hypergraphs. We establish their relationships to lattice animals and network motifs, and we develop their combinatorial properties for sparse and uncorrelated hypergraphs ...
openaire +3 more sources
Of Zoogrammatology:A Derridean theory of textual animality [PDF]
This thesis aims to ‘apply’, as it were, some of Jacques Derrida’s conclusions regarding the age-old distinction between ideal and material to an understanding of animality and how it emerges in texts.
Da Silva, José Rodolfo
core
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source