Results 141 to 150 of about 332,288 (305)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
PERCEPTIONS OF GENETICALLY MODIFIED AND ORGANIC FOODS AND PROCESSES: NORTH DAKOTA COLLEGE STUDENTS [PDF]
Perceptions of genetically modified (GM) and organic food among North Dakota college students were elicited and compared. Participants responded to one of two survey instruments containing identical wording except for reference to genetic modification or
Anderson, Jon C. +2 more
core +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
HAWAII PUBLIC OPINION ON AGRICULTURAL PRODUCTS DERIVED FROM GENETICALLY MODIFIED ORGANISM (GMO) TECHNOLOGY [PDF]
This article studied Hawaii public opinion on agricultural products and processes using GMO technology. We used telephone to interview the people in each island of Hawaii.
Chan-Halbrendt, Catherine +2 more
core +1 more source
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Biotechnology and the Creation of Ethics [PDF]
Biotechnology promises to change the course of evolution. Rather than patiently waiting as natural selection channels the forces of biology into contouring the nature and character of the organisms that populate our world, biotechnology allows humans to ...
Raymond Coletta
core +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Genetically modified animals as models of pulmonary disease.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2002 Improvements in biological research and the development of new techniques for human health protection require animal experimentation of various species. In particular, animal models are always necessary to test new therapies for the treatment of various human diseases. The latest advances in molecular biology involving genetic modification are aimed at
LUNGARELLA G +3 more
openaire +3 more sources
Canadian Consumer Concerns About Food Safety Issues and Confidence in Food Products: Comparison of Beef and Pork [PDF]
In examining consumers’ willingness to pay (WTP) for food attributes, one approach is to use economic experiments, sometimes associated with consumers sensory testing.
Goddard, Ellen W., Muringai, Violet
core +1 more source