Results 161 to 170 of about 175,605 (302)

Knowledge, perspectives, and risk perceptions on gene drive and genetically modified mosquitoes for malaria control among African stakeholders: a scoping review protocol. [PDF]

Syst Rev
Sogodogo A, Diarra S, Keita S, Diallo I, Hartley S, Telly N, Dolo H, Sanogo D, Kané F, Tangara CO, Diakité M, Sangho O, Kayentao K, Fritz H, Winch PJ, Doumbia S.   +15 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Genetically modified animals in research : an analysis of applications submitted to ethics committees on animal experimentation in Sweden

, 2005
The use of genetically modified animals in biomedical research has increased during recent years and its ethical aspects have been subject to academic discussion.
Nordgren, Anders, Röcklinsberg, Helena
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Therapeutic efficacy of genetically engineered neural stem cells in cerebral ischemia: a systematic review and meta-analysis. [PDF]

J Transl Med
Li S, Solis Marzan RA, Wei C, Razak A, Wong CHY, Moore J, McDonald CA.   +6 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Analysis of public perception and socio-demographic drivers of genetically modified organisms in Iran. [PDF]

GM Crops Food
Ahmadabadi M, Dehghanian Z, Valizadeh Kamran R, Pazhouhandeh M, Aryan A.   +4 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Safety evaluation of an extension of use of the food enzyme β-galactosidase from the genetically modified <i>Bacillus licheniformis</i> strain NZYM-BT. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Cavanna D, Liu Y, Tokić V.   +15 more
europepmc   +1 more source

Bioethical analysis of transgenic animals and genetically modified organisms (GMO)

, 2014
The important technological advance in genetic manipulation has led to the development of genetically modified animals. The resulting being is called a transgenic animal.
Capó Martí, Miguel Andrés, Drane, James F., Roa Castellanos, Ricardo, Anadón Baselga, María José   +3 more
core