Results 51 to 60 of about 332,288 (305)
Pharmaceutics, 2020 In vivo gene delivery involves direct injection of nucleic acids (NAs) into tissues, organs, or tail-veins. It has been recognized as a useful tool for evaluating the function of a gene of interest (GOI), creating models for human disease and basic ...
Masahiro Sato +4 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Neural circuits mediating olfactory-driven behavior in fish
Frontiers in Neural Circuits, 2013 The fish olfactory system processes odor signals and mediates behaviors that are crucial for survival such as foraging, courtship and alarm response. Although the upstream olfactory brain areas (olfactory epithelium and olfactory bulb) are well studied ...
Florence eKermen +9 more
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Efficient In Vivo Introduction of Point Mutations Using ssODN and a Co-CRISPR Approach
Biological Procedures Online, 2020 Background The generation of point mutations is a major tool for evaluating the roles of specific nucleotides or amino acids within the regulatory or functional landscape. However, examination of these mutations in vivo requires the generation of animals
Tgst Levi +4 more
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Recent Advances in Genetically Engineered Microorganisms and their Risks: A Review
International Journal on Food, Agriculture and Natural Resources, 2023 Genetically engineered microorganisms have applications in various domains, such as agriculture, bioscience, healthcare, life sciences, and research. The novel methods of the system Clustered Regularly Interspaced Short Palindromic Repeats associated ...
Jiregna Gari +2 more
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Impact of genetically modified organisms on meat quality
Open Veterinary JournalA unique class of gene biotechnology known as genetic modification modifies the genetic makeup of living things like microbes, plants, and animals. Several possible advantages and hazards associated with gene biotechnology. Due to increased food demands
Muntaha Ghazi Hasan
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Ninety-day oral toxicity studies on two genetically modified maize MON810 varieties in Wistar Han RCC rats (EU 7th Framework Programme project GRACE) [PDF]
, 2014 The GMO Risk Assessment and Communication of Evidence (GRACE; www.grace-fp7.eu) project is funded by the European Commission within the 7th Framework Programme.
Ambrušová, Katarína +9 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Multiple gene modifications of pigs for overcoming obstacles of xenotransplantation
National Science Open, 2023 Xenotransplantation, involving animal organ transplantation into humans to address the human organ shortage, has been studied since the 17th century.
Wu Han, Lian Meng, Lai Liangxue
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