Results 31 to 40 of about 175,605 (302)

Breeding and Maintenance of Immunodeficient Mouse Lines under SPF Conditions—A Call for Individualized Severity Analyses and Approval Procedures

Animals, 2021
In the EU, the breeding of genetically modified laboratory animals is, by definition, an animal experiment if the offspring may experience pain, suffering, or harm. In order to determine the actual burden of genetically modified mice, established methods
Thomas Kammertoens, Sarah Jeuthe, Heike Baranzke, Antonina Klippert, Christa Thöne-Reineke   +4 more
doaj   +1 more source

Effects of Feeding Genetically Modified Crops to Domestic Animals: A Review

Turkish Journal of Agriculture: Food Science and Technology, 2019
Genetically modified (GM) crops are being planted at large scale worldwide. In most of the countries, GM crops are processed into livestock feed. The land is used for cultivation of GM plants has been increased in recent years; in 2012 GM plants were ...
Muhammad Zeeshan Akram, Sema Yaman, Hassan Jalal, Sibel Canoğulları Doğan, Sana Shahid, Basit Shaukat Ali   +5 more
doaj   +1 more source

Manipulations with early mouse embryos for generation of genetically modified animals

Вавиловский журнал генетики и селекции, 2017
Recently, genome-editing technologies have  become more efficient and accessible. The discovery of nucleases for directional genome editing (CRISPR/Cas9, TALEN, ZFNs) significantly accelerated and simplified the production of mice with targeted gene ...
A. N. Korablev, I. A. Serova, B. V. Skryabin   +2 more
doaj   +1 more source

Degeneration of Bioprosthetic Heart Valves: Update 2020

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
The implantation of bioprosthetic heart valves (BHVs) is increasingly becoming the treatment of choice in patients requiring heart valve replacement surgery.
Alexander E. Kostyunin, Arseniy E. Yuzhalin, Maria A. Rezvova, Evgeniy A. Ovcharenko, Tatiana V. Glushkova, Anton G. Kutikhin   +5 more
doaj   +1 more source

Immunotoxicological Evaluation of Genetically Modified Rice Expressing Cry1Ab/Ac Protein (TT51-1) by a 6-Month Feeding Study on Cynomolgus Monkeys. [PDF]

PLoS ONE, 2016
The present study was performed to evaluate the food safety of TT51-1, a new type of genetically modified rice that expresses the Cry1Ab/Ac protein (Bt toxin) and is highly resistant to most lepidopteran pests.
Xiaoyan Tan, Xiaobing Zhou, Yao Tang, Jianjun Lv, Lin Zhang, Li Sun, Yanwei Yang, Yufa Miao, Hua Jiang, Gaofeng Chen, Zhiying Huang, Xue Wang   +11 more
doaj   +1 more source

The Online Genetically Modified Food Debate: Sociotechnical Imaginaries and Genetically Modified Animals

, 2021
The aim of this article is to investigate the sociotechnical imaginaries present in UK online news articles and below the line comments in connection with genetically modified animals.
Price, Catherine
core   +1 more source

Danos oxidativos e neurodegeneração: o quê aprendemos com animais transgênicos e nocautes?

Química Nova, 2006
Accumulated evidence indicates that oxidative stress plays a role in neurodegenerative diseases, such as Alzheimer, Parkinson and Amyotrophic Lateral Sclerosis.
Lívea Fujita Barbosa, Marisa H.G. de Medeiros, Ohara Augusto   +2 more
doaj   +1 more source

Dopamine transporter knockout rats as the new preclinical model of hyper- and hypo-dopaminergic disorders

Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2019
Rat line lacking the dopamine transporter (DAT-KO rats) was recently developed. Lack of DAT in these mutants manifests behaviorally as spontaneous hyperactivity and cognitive deficits.
I. Sukhanov, D. Leo, M. A. Tur, I. V. Belozertseva, A. Savchenko, R. R. Gainetdinov   +5 more
doaj   +1 more source

The effects of tail biopsy for genotyping on behavioral responses to nociceptive stimuli. [PDF]

PLoS ONE, 2009
Removal of a small segment of tail at weaning is a common method used to obtain tissue for the isolation of genomic DNA to identify genetically modified mice.
Maria Elena P Morales, Robert W Gereau
doaj   +1 more source

Guidance on the risk assessment of food and feed from genetically modified animals and on animal health and welfare aspects

, 2012
This document provides guidance for the risk assessment of food and feed containing, consisting of or produced from genetically modified (GM) animals, as well as for the health and welfare assessment of these animals, within the framework of Regulation ...
EFSA Panel on Genetically Modified Organisms (GMO), EFSA Panel on Animal Health and Welfare (AHAW)   +1 more
core   +2 more sources