Results 21 to 30 of about 173,056 (260)
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2019 Rat line lacking the dopamine transporter (DAT-KO rats) was recently developed. Lack of DAT in these mutants manifests behaviorally as spontaneous hyperactivity and cognitive deficits.
I. Sukhanov +5 more
doaj +1 more source
Annals of Agricultural and Environmental Medicine, 2017 Introduction Agriculture based on genetically modified organisms plays an increasingly important role in feeding the world population, which is evidenced by a considerable growth in the size of land under genetically modified crops (GM).
Stanisław Lachowski +5 more
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The effects of tail biopsy for genotyping on behavioral responses to nociceptive stimuli. [PDF]
PLoS ONE, 2009 Removal of a small segment of tail at weaning is a common method used to obtain tissue for the isolation of genomic DNA to identify genetically modified mice.
Maria Elena P Morales, Robert W Gereau
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Journal of Animal Reproduction and Biotechnology, 2018 Pigs are considered as optimal donor animal for the successful xenotransplantation. To increase the possibility of clinical application, genetic modification to increase compatibility with human is an important and essential process. Genetic modification
Bumrae Cho +7 more
doaj +1 more source
Simple Genome Editing of Rodent Intact Embryos by Electroporation. [PDF]
PLoS ONE, 2015 The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) system is a powerful tool for genome editing in animals. Recently, new technology has been developed to genetically modify animals without using highly skilled ...
Takehito Kaneko, Tomoji Mashimo
doaj +1 more source
Are good ideas enough?: The impact of socio-economic and regulatory factors on GMO commercialisation
Biological Research, 2013 In recent years scientific literature has seen an increase in publications describing new transgenic applications. Although technically-sound, these promising developments might not necessarily translate into products available to the consumer.
Núria Vàzquez-Salat
doaj +1 more source
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
Pediatric Blood &Cancer, EarlyView.ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
Pharmaceutics, 2020 In vivo gene delivery involves direct injection of nucleic acids (NAs) into tissues, organs, or tail-veins. It has been recognized as a useful tool for evaluating the function of a gene of interest (GOI), creating models for human disease and basic ...
Masahiro Sato +4 more
doaj +1 more source
Genetically Modified Rabbits for Cardiovascular Research
Frontiers in Genetics, 2021 Rabbits are one of the most used experimental animals for investigating the mechanisms of human cardiovascular disease and lipid metabolism because they are phylogenetically closer to human than rodents (mice and rats).
Jianglin Fan +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens +4 more
wiley +1 more source