Results 11 to 20 of about 173,056 (260)

Cutaneous melanoma in genetically modified animals [PDF]

open access: yesPigment Cell Research, 2007
AbstractCutaneous melanomas are tumors originating from skin melanocytes which are present in hair follicles, and interfollicular epidermal and dermal layers. Experimental work in model systems involves in silico, in vitro and in vivo analyses. Such models allow to mimick melanocytic aberrations characteristic of melanoma, and to potentially exploit ...
Larue, L., Beermann, F.
openaire   +2 more sources

Modern approaches to production of safe and effective genetically modified rabies vaccines for animals

open access: yesВетеринария сегодня, 2023
Rabies is a dangerous zoonoticdisease that affects the central nervous system, causes encephalomyelitis and paralyses and Is almost invariably fatal.
M. I. Doronin   +6 more
doaj   +1 more source

Factors Affecting the Adoption of Genetically Modified Animals in the Food and Pharmaceutical Chains

open access: yesBio-based and Applied Economics, 2012
The production of genetically modified (GM) animals is an emerging technique that could potentially impact the livestock and pharmaceutical industries.
Cristina Mora   +6 more
doaj   +1 more source

Breeding and Maintenance of Immunodeficient Mouse Lines under SPF Conditions—A Call for Individualized Severity Analyses and Approval Procedures

open access: yesAnimals, 2021
In the EU, the breeding of genetically modified laboratory animals is, by definition, an animal experiment if the offspring may experience pain, suffering, or harm. In order to determine the actual burden of genetically modified mice, established methods
Thomas Kammertoens   +4 more
doaj   +1 more source

Manipulations with early mouse embryos for generation of genetically modified animals

open access: yesВавиловский журнал генетики и селекции, 2017
Recently, genome-editing technologies have  become more efficient and accessible. The discovery of nucleases for directional genome editing (CRISPR/Cas9, TALEN, ZFNs) significantly accelerated and simplified the production of mice with targeted gene ...
A. N. Korablev   +2 more
doaj   +1 more source

Welfare Issues of Genetically Modified Animals [PDF]

open access: yesILAR Journal, 2002
Genetically engineered animals have opened new frontiers in the study of physiology and disease processes. Mutant animals offer more accurate disease models and increased precision for pathogenesis and treatment studies. Their use offers hope for improved therapy to patients with conditions that currently have poor or ineffective treatments.
openaire   +2 more sources

Prevalence of genetically modified soybean in animal feedingstuffs in Poland [PDF]

open access: yesJournal of Veterinary Research, 2021
Abstract Introduction Globally, genetically modified (GM) crops were grown on 191.7 million hectares in 2018, which were mostly sown with soybean, maize, cotton, oilseed rape, and rice. The most popular traits introduced through genetic modification include herbicide and pest insect resistance.
Sieradzki Zbigniew   +3 more
openaire   +3 more sources

Degeneration of Bioprosthetic Heart Valves: Update 2020

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
The implantation of bioprosthetic heart valves (BHVs) is increasingly becoming the treatment of choice in patients requiring heart valve replacement surgery.
Alexander E. Kostyunin   +5 more
doaj   +1 more source

Immunotoxicological Evaluation of Genetically Modified Rice Expressing Cry1Ab/Ac Protein (TT51-1) by a 6-Month Feeding Study on Cynomolgus Monkeys. [PDF]

open access: yesPLoS ONE, 2016
The present study was performed to evaluate the food safety of TT51-1, a new type of genetically modified rice that expresses the Cry1Ab/Ac protein (Bt toxin) and is highly resistant to most lepidopteran pests.
Xiaoyan Tan   +11 more
doaj   +1 more source

Danos oxidativos e neurodegeneração: o quê aprendemos com animais transgênicos e nocautes?

open access: yesQuímica Nova, 2006
Accumulated evidence indicates that oxidative stress plays a role in neurodegenerative diseases, such as Alzheimer, Parkinson and Amyotrophic Lateral Sclerosis.
Lívea Fujita Barbosa   +2 more
doaj   +1 more source

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