Results 241 to 250 of about 7,438,473 (359)

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

A Retrospective Study of Suspected Animal Abuse Cases in Trinidad and Tobago, 2008-2025. [PDF]

Animals (Basel)
Frontera-Acevedo K, Boodram A, Luke X, Phillip E, Suepaul R, Gyan L.   +5 more
europepmc   +1 more source

Laboratory Animals Protection Bill

, 1979

core  

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

High sensitivity of the Bionote Anigen Rapid Rabies Antigen Test in detection of diverse rabies virus variants suggests utility for global rabies control. [PDF]

J Clin Microbiol
Orciari LA, Wicker V, Bonaparte S, Yager PA, Hartloge C, Silas K, Seiders M, Patel P, Regec A, Maldonado-Cedeño M, Flores Ramos RF, Messenger S, Lopez R, Preas C, Price A, Beckmen KB, Campbell KE, Goff M, Vogt C, Wingerter L, Schwarzkopf KL, Mulugeta Y, Fujaga DS, Fields T, Dautu G, Dilius P, Gigante C, Condori RE, Hutson CL, Satheshkumar PS, Wallace RM.   +30 more
europepmc   +1 more source

The Welfare of Laboratory Animals

, 2007
Kaliste, Eila
core   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Correction: Sleep-wake patterns are altered with age, Prdm13 signaling in the DMH and diet restriction in mice. [PDF]

Life Sci Alliance
Tsuji S, Brace CS, Yao R, Tanie Y, Tada H, Rensing N, Mizuno S, Almunia J, Kong Y, Nakamura K, Furukawa T, Ogiso N, Toyokuni S, Takahashi S, Wong M, Imai SI, Satoh A.   +16 more
europepmc   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Rabies in a dog commercially imported into Germany from Russia, 2026. [PDF]

Euro Surveill
Freuling CM, Rogoll L, Calvelage S, Höper D, Ushakov D, Rzepa L, Schmid L, Finke S, Klingelhöfer I, Larres G, Krüger C, Steinhauer D, Eisch-Wolf S, Dehler M, Sauter-Louis C, Mueller T.   +15 more
europepmc   +1 more source