Results 131 to 140 of about 1,389,519 (208)
The administration of „Apifitostimulin” in gestating sows led to increase of the immunobiological status of newborn pigs. At the 3rd day of their life the increase of immunoglobulins IgA, IgG, IgM and T-Lymphocytes in serum was registered to compare ...
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doaj
Identification of de‑epithelized structures of pig placenta
The article presents the structural features of dе-epithelized structures in the placenta of sows. A systematic histological examination of placentas in pregnant animals allowed us to identify new methods for assessing their condition, taking into ...
Alexander V. Agarkov +4 more
doaj +1 more source
Using Tandem Mass Spectrometry for Metabolic Disease Screening Among Newborns; a Report of a Work Group [PDF]
Increasingly, tandem mass spectrometry (MS/MS) is being used for newborn screening because this laboratory testing technology substantially increases the number of metabolic disorders that can be detected from dried blood-spot specimens.
core
An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu +7 more
wiley +1 more source
Astrovirus infection in animals (literature review)
Viral agents are a major cause of mass gastroenteritides in newborn calves in the countries around the world. Early postnatal diarrhea as the main reason of morbidity and mortality in young animals leads to serious problems in the commercial livestock ...
V. A. Mischenko +3 more
doaj +1 more source
Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng +14 more
wiley +1 more source
The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi +6 more
wiley +1 more source
Cross sectional, community based study of care of newborn infants in Nepal [PDF]
Objective To determine home based newborn care practices in rural Nepal in order to inform strategies to improve neonatal outcome.Design Cross sectional, retrospective study using structured interviews.Setting Makwanpur district, Nepal.Participants 5411 ...
Osrin, D +8 more
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CYYR1 as an epigenetically dysregulated tumor‐suppressive factor that influences oncoprotein stability through TRIM21‐dependent HMMR regulation and reveals a potential therapeutic vulnerability in CYYR1‐deficient LUAD. The graphical illustration was created using FigDraw (www.figdraw.com).
Fengsheng Dai +15 more
wiley +1 more source
GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko +5 more
wiley +1 more source

