Results 161 to 170 of about 1,457,674 (303)

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

Overcoming doramectin failure: field efficacy of pour-on 5% fluralaner and an experimental 1% oral formulation for the prevention of Cochliomyia hominivorax-associated umbilical myiasis in newborn calves. [PDF]

Parasit Vectors
de Freitas MDB, Rodrigues DC, de Paiva PEM, Torres S, Borges FA.   +4 more
europepmc   +1 more source

Sequential Patterning of Photoresponsive Hydrogels Directs Crypt Fission and Reveals the Role of Epithelial Curvature on Fission Symmetry

Advanced Science, EarlyView.
Deterministic crypt fission is achieved in intestinal organoids using photopatternable hydrogels with spatiotemporal control. Daughter‐crypt symmetry is shown to depend on parent‐crypt geometry and epithelial curvature, while myosin‐dependent mechanosensing links tissue shape to regenerative outcomes.
Delaney L. McNally, Kaustav Bera, Nolan R. Petrich, Alex Khang, Marilyne Coulombe, David Castillo‐Azofeifa, Ophir D. Klein, Peter J. Dempsey, Kristi S. Anseth   +8 more
wiley   +1 more source

Feeding the newborn: comparative problems in man and animals [PDF]

Proceedings of the Nutrition Society, 1974
openaire   +2 more sources

A pantothenic acid deficiency outbreak causing mortality and neuromuscular disorders in newborn and nursery piglets. [PDF]

Porcine Health Manag
Loscertales SI, Romagosa A, Martino L, Cid-Cañete M, Bosco S, Leiva-Forns M, Segalés J.   +6 more
europepmc   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Influence of parity on gestational and perinatal parameters of jennies of the Nordestino ecotype. [PDF]

Vet Anim Sci
de Farias IM, Santiago JM, de Sobral GG, da Silva AH, Felix NA, Pinto DSA, de Melo Júnior EF, da Silva KML, Carneiro GF, Maia VN, Pinto APG, da Rocha LL, Gonzaga IVF, Taran FMP, Lucena JEC.   +14 more
europepmc   +1 more source

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

Perinatal physiology and welfare in water buffalo: calving, mother-calf bonding, lactation, and postpartum disorders. [PDF]

Front Vet Sci
Mota-Rojas D, Napolitano F, Fischer V, Bettencourt AF, Álvarez-Macías A, Hernández-Avalos I, Villanueva-García D, Cruz-Monterrosa R, Ramírez-Bribiesca JE, Domínguez-Oliva A, Olmos-Hernández A, Reyes-Sotelo B, Torres-Bernal F, Minervino AHH.   +13 more
europepmc   +1 more source

Other title: Financial Review

, 2010
application/pdf; "December 13-14, 2010."; Includes bibliographical references."A Newborn Screening Financial Review Team...met with selected staff members of the newborn screening program of the Kansas Department of Health and Environment (
National Newborn Screening & Genetics Resource Center (U.S.)
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