Results 91 to 100 of about 1,833,719 (312)

Social behavior of domestic dogs and cats as compared to wild canine and feline species : an honors thesis (HONRS 499) [PDF]

open access: yes, 1995
With the help of animal behavioralists, parallels have been drawn between domestic dogs and cats and their wild cousins. In some respects, social behavior in domestic animals has remained similar to characteristics found in wild animals.
Rusk, Anthony W.
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

GABAergic compensation in connexin36 knock-out mice evident during low-magnesium seizure-like event activity [PDF]

open access: yes, 2010
Gap junctions within the cerebral cortex may facilitate cortical seizure formation by their ability to synchronize electrical activity. To investigate this, one option is to compare wild-type (WT) animals with those lacking the gene for connexin36 (Cx36 ...
Jacobson, Gregory M.   +3 more
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Exotic and invasive terrestrial and freshwater animal species in the Dutch Caribbean [PDF]

open access: yes
An overview of 72 invasive animals of the terrestrial and freshwater environments of the Dutch Caribbean, eleven of which are no longer present. All invasive animals that are principally agricultural pests and or animal and plant diseases (46 species ...
Buurt, G., van, Debrot, A.O.
core   +1 more source

High-Speed Rail and Equine Issues [PDF]

open access: yes, 2015
Community concerns have been raised about the possible negative impacts of high-speed rail (HSR) service on equestrian areas. Although much is known about the impact of aircraft noise on wild and domestic animals, relatively little information is ...
Haas, Peter J, Scrivener, Allie
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Phytochemistry and Pharmacology of Sesquiterpenoids from Atractylodes DC. Genus Rhizomes

open access: yesMolecules
The rhizomes of the genus Atractylodes DC. consist of various bioactive components, including sesquiterpenes, which have attracted a great deal of research interest in recent years.
Zhengyi Qu   +5 more
doaj   +1 more source

Application of stable isotope analysis to differentiate shrimp extracted by industrial fishing or produced through aquaculture practices. [PDF]

open access: yes, 2014
Carbon and nitrogen stable isotope values were determined in Pacific white shrimp (Litopenaeus vannamei) with the objective of discriminating animals produced through aquaculture practices from those extracted from the wild.
Cruz Suárez, Lucía Elizabeth   +5 more
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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