Results 81 to 90 of about 1,122,045 (313)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Eating wild animals: rewards, risks and recommendations [PDF]

open access: yes
During the COVID-19 pandemic, prominent calls were made in the Global North to end the hunting, selling and eating of meat from wild animals. This report is a partial response to such calls, arguing that such a ban would be both impossible and arguably ...
Bett, Bernard K.   +12 more
core  

Perspectives of genomics for genetic conservation of livestock

open access: yes, 2010
Genomics provides new opportunities for conservation genetics. Conservation genetics in livestock is based on estimating diversity by pedigree relatedness and managing diversity by choosing those animals that maximize genetic diversity.
Windig, J.J., Engelsma, K.A.
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The Diagnostic Value of qPCR Quantification of Paenibacillus larvae in Hive Debris and Adult Bees for Predicting the Onset of American Foulbrood

open access: yesVeterinary Sciences
American foulbrood (AFB) is a serious infectious disease of honeybees (Apis mellifera) caused by Paenibacillus larvae. Increased P. larvae count in hive-related material is associated with an increased risk of AFB. Here, we quantified P.
Bojan Papić   +7 more
doaj   +1 more source

Tuberculosis in Captive Wild Animals [PDF]

open access: yesJournal of Hygiene, 1928
The results of this investigation show that tuberculosis in captive wild mammals may be caused by any one of the three types of tubercle bacilli—human, bovine or avian.In the Primates, which under experimental conditions are susceptible in an equal degree to bovine and human tubercle bacilli, natural tuberculosis may result from infection with either ...
openaire   +2 more sources

Comparative mortality levels among selected species of captive animals [PDF]

open access: yes
We present life tables by single year of age and sex for groups of animals and for 42 individual mostly mammalian species. Data are derived from the International Species Information System. The survivorship of most of these species has never been mapped
Samuel Preston   +2 more
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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