Results 111 to 120 of about 4,965,699 (338)
, 2018 Biological invasions are one of the great threats to Earth’s ecosystems and biodiversity in the Anthropocene. However, species introductions and invasions extend deep into the human past, with the translocation of both wild and domestic species around ...
Courtney A. Hofman, T. Rick
semanticscholar +1 more source
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
Parasite spill-back from domestic hosts may induce an Allee effect in wildlife hosts [PDF]
, 2012 The exchange of native pathogens between wild and domesticated animals can lead to novel disease dynamics. A simple model reveals that the spill-back of native parasites\ud from domestic to wild hosts may cause a demographic Allee effect.
Ashander, J., Krkošek, M., Lewis, M. A.
core +1 more source
Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design
FEBS Letters, EarlyView.Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos +3 more
wiley +1 more source
Parasites & Vectors, 2016 In recent years, the scope and importance of emergent vector-borne diseases has increased dramatically. In Algeria, only limited information is currently available concerning the presence and prevalence of these zoonotic diseases.
H. Leulmi +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
The prevalence of Coxiella burnetii in ticks and animals in Slovenia
BMC Veterinary Research, 2019 Background The obligate intracellular bacterium Coxiella burnetii causes globally distributed zoonotic Q fever. Ruminant livestock are common reservoirs of C. burnetii.
Nataša Knap +4 more
doaj +1 more source
Butterflies, Magic Carpets, and Scary Wild Animals: An Intervention with a Young Gymnast [PDF]
, 2016 This article presents a reflective case example of a sport psychology consultation carried out with a 9-year-old gymnast during the final year of the consultant’s training to become a British Psychological Society (BPS) chartered sport psychologist ...
Howells, Karen
core
Measuring Animal Age with DNA Methylation: From Humans to Wild Animals
Frontiers in Genetics, 2017 DNA methylation (DNAm) is a key mechanism for regulating gene expression in animals and levels are known to change with age. Recent studies have used DNAm changes as a biomarker to estimate chronological age in humans and these techniques are now also ...
Ricardo De Paoli-Iseppi +5 more
semanticscholar +1 more source