Results 91 to 100 of about 6,059,454 (285)

The impact of anaesthesia upon the main functions of the animal organism [PDF]

Medicamentul Veterinar, 2007
The general anesthetics produce the reversible loss of consciousness and sensitivity and influence the vital functions of the organism. More than a century ago, the anesthetic was considered to be a poison which intoxicates the nervous system.
Năstasă V.,, Mariana Grecu
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Perspectives on Environmental Humanities: Technology, Nature, and Human-Animal Relationships

Svetovi
Finn Arne Jørgensen is a professor of environmental history at the University of Stavanger in Norway. He studies the evolution of human relationships with nature over time and place.
Gašper Raušl, Finn Arne Jørgensen
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Minimally Invasive Surgical Techniques for the Treatment of Dogs with Urinary Incontinence Due to Ureteral Ectopia

Life
Ectopic ureters are uncommon congenital abnormalities in dogs, leading to urinary incontinence. Ectopic ureters can be intramural or extramural. Intramural is usually the more prevalent form. Female dogs are affected more often than male dogs.
Przemysław Prządka, Bartłomiej Liszka, Wojciech Krajewski, Sylwester Gerus, Ludwika Gąsior, Agnieszka Antończyk, Piotr Skrzypczak, Dominika Kubiak-Nowak, Mateusz Hebel, Kamil Suliga, Zdzisław Kiełbowicz, Dariusz Patkowski   +11 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Hypergraph animals

Physical Review E
Here we introduce simple structures for the analysis of complex hypergraphs, hypergraph animals. These structures are designed to describe the local node neighbourhoods of nodes in hypergraphs. We establish their relationships to lattice animals and network motifs, and we develop their combinatorial properties for sparse and uncorrelated hypergraphs ...
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The tiny giants of regeneration: MSC-derived extracellular vesicles as next-generation therapeutics

Frontiers in Cell and Developmental Biology
Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) are revolutionizing the field of regenerative medicine, becoming the core carriers of next-generation acellular therapeutic strategies.
Tianhe Zhang, Liang Zhang, Xiaoxue Ma, Wenliang Song   +3 more
doaj   +1 more source

Animals and Animals

Between the Species: An Online Journal for the Study of Philosophy and Animals, 2010
Speciesism is the wrong of not acknowledging the moral qualities that non-human animals possess that are similar or equivalent or even superior to the moral qualities that human beings possess. However, since it is manifestly clear that no one thinks that apes are in any way obligated to human beings, it clearly cannot be a form of speciesism to be ...
openaire   +3 more sources